Hs06906401_cn

• Gene Symbol: ACO1
• Assay Reference Genome Location: Chr.9:32389187 on build GRCh38
• Cytoband: 9p21.1

Target Gene Details

• Entrez Gene ID: 48
• Gene Name: aconitase 1
• Gene Aliases: ACONS, HEL60, IREB1, IREBP, IREBP1, IRP1
• Location: Chr.9:32384603-32450836 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ACO1	NM_001278352.1			NP_001265281.1
	NM_002197.2			NP_002188.1
	XM_005251476.1			XP_005251533.1
	AB209480.1			BAD92717.1
	AF261088.1			AAF99681.1
	AK057904.1
	AK308752.1
	BP287929.1
	DA103947.1
	DA409113.1
	DA780353.1
	Z11559.1			CAA77651.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1020675	Chr.9:32323273 - 32391249 on Build GRCh38	Loss	ACO1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein

Gene Ontology Categories:

Process(es)

tricarboxylic acid cycle
citrate metabolic process
regulation of translation
cellular iron ion homeostasis
post-embryonic development
response to iron(II) ion
intestinal absorption

Function(s)

RNA binding
aconitate hydratase activity
protein binding
iron-responsive element binding
metal ion binding
4 iron, 4 sulfur cluster binding