Hs06955385_cn

• Gene Symbol: TXNRD1
• Assay Reference Genome Location: Chr.12:104216117 on build GRCh38
• Cytoband: 12q23.3

Target Gene Details

• Entrez Gene ID: 7296
• Gene Name: thioredoxin reductase 1
• Gene Aliases: GRIM-12, TR, TR1, TRXR1, TXNR
• Location: Chr.12:104215779-104350307 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TXNRD1	NM_001093771.2			NP_001087240.1
	AK304241.1
	AY057105.1			AAL15432.1
	BG772375.1
	DC418649.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3630630	Chr.12:104203244 - 104250924 on Build GRCh38	Loss	TXNRD1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

reductase

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
mesoderm formation
selenium compound metabolic process
signal transduction
cell proliferation
nucleobase-containing small molecule interconversion
cell redox homeostasis
oxidation-reduction process
cellular oxidant detoxification

Function(s)

thioredoxin-disulfide reductase activity
protein binding
electron carrier activity
protein disulfide oxidoreductase activity
flavin adenine dinucleotide binding
methylselenol reductase activity
methylseleninic acid reductase activity