Hs06960445_cn

• Gene Symbol: SCARB1
• Assay Reference Genome Location: Chr.12:124779383 on build GRCh38
• Cytoband: 12q24.31

Target Gene Details

• Entrez Gene ID: 949
• Gene Name: scavenger receptor class B member 1
• Gene Aliases: CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1
• Location: Chr.12:124777628-124863973 on Build GRCh38
• Assay Gene Location: Within Intron 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SCARB1	NM_001082959.1			NP_001076428.1
	NM_005505.4			NP_005496.4
	BC080647.1			AAH80647.1
	BC093732.1			AAH93732.1
	BC112037.1			AAI12038.1
	BC143319.1
	Z22555.1			CAA80277.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv560595	Chr.12:124737381 - 125019207 on Build GRCh38	Gain	UBC BRI3BP SCARB1 MIR5188 TRF-GAA1-4 DHX37
nsv560543	Chr.12:124496040 - 124781090 on Build GRCh38	Gain	SCARB1 NCOR2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane trafficking regulatory protein

Gene Ontology Categories:

Process(es)

endothelial cell proliferation
androgen biosynthetic process
cholesterol catabolic process
receptor-mediated endocytosis
positive regulation of endothelial cell migration
positive regulation of triglyceride biosynthetic process
positive regulation of cholesterol storage
regulation of phosphatidylcholine catabolic process
phospholipid transport
lipopolysaccharide transport
lipopolysaccharide-mediated signaling pathway
detection of lipopolysaccharide
cholesterol efflux
high-density lipoprotein particle remodeling
low-density lipoprotein particle clearance
high-density lipoprotein particle clearance
vitamin transmembrane transport
wound healing
lipoprotein metabolic process
cholesterol homeostasis
blood vessel endothelial cell migration
recognition of apoptotic cell
reverse cholesterol transport
adhesion of symbiont to host
viral entry into host cell
regulation of phagocytosis
intestinal absorption
positive regulation of nitric-oxide synthase activity
triglyceride homeostasis
cholesterol import

Function(s)

lipopolysaccharide binding
virus receptor activity
phosphatidylserine binding
lipopolysaccharide receptor activity
transporter activity
protein binding
1-phosphatidylinositol binding
high-density lipoprotein particle binding
low-density lipoprotein particle binding
apolipoprotein binding
apolipoprotein A-I binding
protein homodimerization activity
high-density lipoprotein particle receptor activity