Hs06964328_cn

• Gene Symbol: TRHDE
• Assay Reference Genome Location: Chr.12:72092936 on build GRCh38
• Cytoband: 12q21.1

Target Gene Details

• Entrez Gene ID: 29953
• Gene Name: thyrotropin releasing hormone degrading enzyme
• Gene Aliases: PAP-II, PGPEP2, TRH-DE
• Location: Chr.12:72087288-72666662 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRHDE	XM_017019244.1			XP_016874733.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv518498	Chr.12:71913836 - 72114999 on Build GRCh38	Loss	TBC1D15 TPH2 TRHDE
esv2422452	Chr.12:72092153 - 72781801 on Build GRCh38	Duplication	TRHDE-AS1 TRHDE

More Information

Additional Information:

For this assay, SNP(s) [rs149449165] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

proteolysis
signal transduction
cell-cell signaling
regulation of blood pressure
peptide catabolic process

Function(s)

aminopeptidase activity
zinc ion binding
peptide binding
metalloaminopeptidase activity