Hs06971811_cn

• Gene Symbol: PDE3A
• Assay Reference Genome Location: Chr.12:20399758 on build GRCh38
• Cytoband: 12p12.2

Target Gene Details

• Entrez Gene ID: 5139
• Gene Name: phosphodiesterase 3A
• Gene Aliases: CGI-PDE, CGI-PDE A, CGI-PDE-A, HTNB
• Location: Chr.12:20369245-20684107 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PDE3A	NM_000921.4			NP_000912.3
	XM_017019420.1			XP_016874909.1
	AJ005036.1			CAA06304.1
	BC117369.1
	BC117371.1
	M91667.2			AAA35912.2
	U36798.1			AAB18673.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1042315	Chr.12:20378707 - 20476932 on Build GRCh38	Gain	PDE3A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

oocyte maturation
cAMP catabolic process
lipid metabolic process
diterpenoid metabolic process
cAMP-mediated signaling
cGMP-mediated signaling
regulation of meiotic nuclear division
response to drug
negative regulation of apoptotic process
negative regulation of vascular permeability
positive regulation of vascular permeability
response to cAMP
positive regulation of oocyte development
cellular response to cGMP
cellular response to transforming growth factor beta stimulus

Function(s)

3',5'-cyclic-AMP phosphodiesterase activity
cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
cAMP binding
metal ion binding
3',5'-cyclic-GMP phosphodiesterase activity