Hs07068813_cn

• Gene Symbol: PRKD1
• Assay Reference Genome Location: Chr.14:29580971 on build GRCh38
• Cytoband: 14q12

Target Gene Details

• Entrez Gene ID: 5587
• Gene Name: protein kinase D1
• Gene Aliases: PKC-MU, PKCM, PKD, PRKCM
• Location: Chr.14:29576479-29927693 on Build GRCh38
• Assay Gene Location: Within Intron 21

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRKD1	NM_002742.2			NP_002733.2
	XM_005267859.1			XP_005267916.1
	XM_011536964.2			XP_011535266.1
	XM_011536965.2			XP_011535267.1
	XM_017021461.1			XP_016876950.1
	XM_017021462.1			XP_016876951.1
	AK314170.1
	X75756.1			CAA53384.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526536	Chr.14:28322483 - 30669172 on Build GRCh38	Gain	FOXG1-AS1 G2E3 SCFD1 LOC105370424 FOXG1 PRKD1 LINC01551
nsv564160	Chr.14:29030900 - 29631166 on Build GRCh38	Gain	PRKD1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

angiogenesis
positive regulation of endothelial cell proliferation
protein phosphorylation
apoptotic process
inflammatory response
Golgi organization
signal transduction
integrin-mediated signaling pathway
Ras protein signal transduction
cell proliferation
positive regulation of endothelial cell migration
regulation of keratinocyte proliferation
positive regulation of neuron projection development
peptidyl-serine phosphorylation
sphingolipid biosynthetic process
regulation of protein stability
positive regulation of CREB transcription factor activity
positive regulation of peptidyl-serine phosphorylation
cellular response to oxidative stress
intracellular signal transduction
cellular response to vascular endothelial growth factor stimulus
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of blood vessel endothelial cell migration
innate immune response
positive regulation of osteoblast differentiation
positive regulation of angiogenesis
negative regulation of endocytosis
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
Golgi vesicle transport
positive regulation of NF-kappaB transcription factor activity
regulation of release of sequestered calcium ion into cytosol
negative regulation of cell death
protein kinase D signaling
positive regulation of histone deacetylase activity
positive regulation of endothelial cell chemotaxis
regulation of integrin-mediated signaling pathway

Function(s)

protein serine/threonine kinase activity
protein kinase C activity
protein binding
ATP binding
kinase activity
identical protein binding
metal ion binding