Hs07070273_cn

• Gene Symbol: SERPINA3
• Assay Reference Genome Location: Chr.14:94613864 on build GRCh38
• Cytoband: 14q32.13

Target Gene Details

• Entrez Gene ID: 12
• Gene Name: serpin family A member 3
• Gene Aliases: AACT, ACT, GIG24, GIG25
• Location: Chr.14:94612377-94624053 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERPINA3	NM_001085.4			NP_001076.2
	AB209060.1			BAD92297.1
	AK093049.1
	AK123091.1	2	571
	AK308565.1	2	572
	AY513275.1			AAT08028.1
	AY513276.1			AAT08029.1
	BC003559.1
	BC010530.1			AAH10530.1
	BC034554.1			AAH34554.1
	BC070265.1			AAH70265.1
	BG565041.1
	CB111903.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470662	Chr.14:94296542 - 94798793 on Build GRCh38	Gain	SERPINA1 SERPINA3 SERPINA4 SERPINA2 SERPINA12 GSC SERPINA11 SERPINA9 SERPINA13P SERPINA5 SERPINA6
nsv565623	Chr.14:94393116 - 94635006 on Build GRCh38	Gain	SERPINA3 SERPINA4 SERPINA12 SERPINA11 SERPINA9 SERPINA5
nsv832865	Chr.14:94499457 - 94667894 on Build GRCh38	Gain	SERPINA3 SERPINA4 SERPINA12 SERPINA13P SERPINA5
esv3635384	Chr.14:94569665 - 94707857 on Build GRCh38	Gain	SERPINA3 SERPINA4 SERPINA13P SERPINA5

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

platelet degranulation
acute-phase response
inflammatory response
negative regulation of endopeptidase activity
regulation of lipid metabolic process
maintenance of gastrointestinal epithelium

Function(s)

DNA binding
serine-type endopeptidase inhibitor activity
protein binding