Hs07131447_cn

• Gene Symbol: URI1
• Assay Reference Genome Location: Chr.19:29977779 on build GRCh38
• Cytoband: 19q12

Target Gene Details

• Entrez Gene ID: 8725
• Gene Name: URI1, prefoldin like chaperone
• Gene Aliases: C19orf2, NNX3, PPP1R19, RMP, URI
• Location: Chr.19:29923644-30016612 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
URI1	NM_001252641.1			NP_001239570.1
	NM_003796.3			NP_003787.2
	NR_045557.1
	XM_005259362.2			XP_005259419.1
	XM_005259363.4			XP_005259420.1
	XM_011527435.1			XP_011525737.1
	AF091095.1			AAD08679.1
	AK001437.1
	AK226173.1
	AK292170.1
	AK314313.1
	BC026184.2			AAH26184.2
	BC067259.1			AAH67259.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063678	Chr.19:29937920 - 29987524 on Build GRCh38	Loss	URI1
dgv3512n100	Chr.19:29974636 - 30013166 on Build GRCh38	Loss	URI1
nsv579283	Chr.19:29974289 - 30048552 on Build GRCh38	Loss	URI1
dgv3510n100	Chr.19:29961142 - 30020645 on Build GRCh38	Loss	URI1
nsv579282	Chr.19:29960594 - 30000137 on Build GRCh38	Loss	URI1
dgv3511n100	Chr.19:29964373 - 29988391 on Build GRCh38	Loss	URI1
dgv3509n100	Chr.19:29954152 - 30028098 on Build GRCh38	Loss	URI1

More Information

Additional Information:

For this assay, SNP(s) [rs77841415] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of cell growth
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
response to virus
negative regulation of phosphatase activity
cellular response to growth factor stimulus
cellular response to steroid hormone stimulus
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

RNA polymerase II transcription corepressor activity
chromatin binding
protein phosphatase inhibitor activity
protein binding
phosphatase inhibitor activity
phosphoprotein binding