Hs07226357_cn

• Gene Symbol: SIN3A
• Assay Reference Genome Location: Chr.15:75370651 on build GRCh38
• Cytoband: 15q24.2

Target Gene Details

• Entrez Gene ID: 25942
• Gene Name: SIN3 transcription regulator family member A
• Gene Aliases: -
• Location: Chr.15:75369379-75455819 on Build GRCh38
• Assay Gene Location: Within Exon 26

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SIN3A	NM_001145357.1	21	5332	NP_001138829.1
	NM_001145358.1	21	5507	NP_001138830.1
	NM_015477.2	21	5409	NP_056292.1
	XM_006720465.3	21	5215	XP_006720528.1
	XM_006720466.3	22	5605	XP_006720529.1
	XM_006720467.3	23	5423	XP_006720530.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv2621n100	Chr.15:75101872 - 75382048 on Build GRCh38	Gain	MIR631 COMMD4 GOLGA6C NEIL1 C15orf39 MAN2C1 GOLGA6D LOC105376731 SIN3A
esv3636926	Chr.15:75363580 - 75378339 on Build GRCh38	Gain	MAN2C1 SIN3A
esv2749894	Chr.15:75326873 - 75749895 on Build GRCh38	Deletion	MIR631 COMMD4 CSPG4 ODF3L1 IMP3 PTPN9 DNM1P35 SNX33 NEIL1 SNUPN MAN2C1 LOC107984799 SIN3A
nsv1615	Chr.15:75351396 - 75377578 on Build GRCh38	Insertion	MIR631 NEIL1 MAN2C1 SIN3A

More Information

Additional Information:

• Set Membership: Intragenic, Exonic, DGV Variation, Validated

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
activation of innate immune response
positive regulation of defense response to virus by host
hematopoietic progenitor cell differentiation
DNA replication
transcription, DNA-templated
protein deacetylation
aging
regulation of hormone levels
positive regulation of G2/M transition of mitotic cell cycle
histone deacetylation
positive regulation of chromatin silencing
cellular protein localization
negative regulation of circadian rhythm
negative regulation of apoptotic process
regulation of transcription from RNA polymerase II promoter in response to oxidative stress
cellular lipid metabolic process
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
response to methylglyoxal
cellular response to glucose stimulus
negative regulation of protein localization to nucleus
negative regulation of histone H3-K27 acetylation
cellular response to dopamine
negative regulation of transcription regulatory region DNA binding

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
RNA polymerase II repressing transcription factor binding
RNA polymerase II transcription corepressor activity
chromatin binding
transcription factor activity, sequence-specific DNA binding
RNA binding
histone deacetylase activity
protein binding
protein complex binding
protein deacetylase activity