Hs07441764_cn

• Gene Symbol: ZEB1
• Assay Reference Genome Location: Chr.10:31321941 on build GRCh38
• Cytoband: 10p11.22

Target Gene Details

• Entrez Gene ID: 6935
• Gene Name: zinc finger E-box binding homeobox 1
• Gene Aliases: AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A
• Location: Chr.10:31318495-31529814 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZEB1	NM_001128128.2			NP_001121600.1
	NM_001174093.1			NP_001167564.1
	NM_001174094.1			NP_001167565.1
	NM_001174095.1			NP_001167566.1
	NM_001174096.1			NP_001167567.1
	NM_001323638.1			NP_001310567.1
	NM_001323641.1			NP_001310570.1
	NM_001323642.1			NP_001310571.1
	NM_001323643.1			NP_001310572.1
	NM_001323644.1			NP_001310573.1
	NM_001323645.1			NP_001310574.1
	NM_001323646.1			NP_001310575.1
	NM_001323647.1			NP_001310576.1
	NM_001323648.1			NP_001310577.1
	NM_001323649.1			NP_001310578.1
	NM_001323650.1			NP_001310579.1
	NM_001323651.1			NP_001310580.1
	NM_001323652.1			NP_001310581.1
	NM_001323653.1			NP_001310582.1
	NM_001323654.1			NP_001310583.1
	NM_001323655.1			NP_001310584.1
	NM_001323656.1			NP_001310585.1
	NM_001323657.1			NP_001310586.1
	NM_001323658.1			NP_001310587.1
	NM_001323659.1			NP_001310588.1
	NM_001323660.1			NP_001310589.1
	NM_001323661.1			NP_001310590.1
	NM_001323662.1			NP_001310591.1
	NM_001323663.1			NP_001310592.1
	NM_001323664.1			NP_001310593.1
	NM_001323665.1			NP_001310594.1
	NM_001323666.1			NP_001310595.1
	NM_001323671.1			NP_001310600.1
	NM_001323672.1			NP_001310601.1
	NM_001323673.1			NP_001310602.1
	NM_001323674.1			NP_001310603.1
	NM_001323675.1			NP_001310604.1
	NM_001323676.1			NP_001310605.1
	NM_001323677.1			NP_001310606.1
	NM_001323678.1			NP_001310607.1
	NM_030751.5			NP_110378.3
	XM_006717498.2			XP_006717561.1
	XM_011519643.2			XP_011517945.1
	XM_017016597.1			XP_016872086.1
	AK091478.1			BAC03673.1
	AK294775.1
	AK296244.1
	AK299541.1
	AK299666.1
	AK300830.1
	AK307510.1
	AK308785.1
	AK308822.1
	AK309331.1
	AK309399.1
	AK310924.1
	AK311116.1
	AK311137.1
	AK311187.1
	AK311201.1
	AK311372.1
	AK311557.1
	AK314683.1
	AL831979.1
BC009572.1
BC107781.1			AAI07782.1
BC112392.1			AAI12393.1
BX647794.1
BX954549.1
DB276952.1
DB442432.1
DC299346.1
DC375708.1
DC403144.1
U12170.1			AAA20602.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831824	Chr.10:31290791 - 31340754 on Build GRCh38	Loss	ZEB1 ZEB1-AS1
dgv701n100	Chr.10:31321504 - 31388389 on Build GRCh38	Loss	ZEB1 LOC100505502

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
immune response
pattern specification process
central nervous system development
cell proliferation
negative regulation of cell proliferation
regulation of mesenchymal cell proliferation
regulation of transforming growth factor beta receptor signaling pathway
negative regulation of epithelial cell differentiation
regulation of T cell differentiation in thymus
positive regulation of neuron differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic camera-type eye morphogenesis
embryonic skeletal system morphogenesis
semicircular canal morphogenesis
regulation of smooth muscle cell differentiation
cartilage development
cellular response to amino acid stimulus
cochlea morphogenesis

Function(s)

transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
transcription corepressor activity
protein binding
transcription factor binding
zinc ion binding
E-box binding