Hs07535494_cn

• Gene Symbol: CDH4
• Assay Reference Genome Location: Chr.20:61252606 on build GRCh38
• Cytoband: 20q13.33

Target Gene Details

• Entrez Gene ID: 1002
• Gene Name: cadherin 4
• Gene Aliases: CAD4, R-CAD, RCAD
• Location: Chr.20:61252426-61940617 on Build GRCh38
• Assay Gene Location: Overlaps Exon 1 - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDH4	NM_001794.4			NP_001785.2
	AK315192.1
	BC101651.1			AAI01652.1
	BC112150.1			AAI12151.1
	L34059.1			AAA35627.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv7640n54	Chr.20:61252569 - 61253373 on Build GRCh38	Gain	CDH4
nsv586426	Chr.20:61252337 - 61253373 on Build GRCh38	Loss	CDH4
dgv7639n54	Chr.20:61252123 - 61253373 on Build GRCh38	Gain+Loss	CDH4
dgv7637n54	Chr.20:61252058 - 61253373 on Build GRCh38	Gain	CDH4
nsv1073074	Chr.20:61251943 - 61253344 on Build GRCh38	Deletion	CDH4
esv29173	Chr.20:61252096 - 61253459 on Build GRCh38	Loss	CDH4
nsv828767	Chr.20:61247659 - 61259003 on Build GRCh38	Gain	CDH4

More Information

Additional Information:

For this assay, SNP(s) [rs111910331] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cadherin

Gene Ontology Categories:

Process(es)

cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
axon guidance
adherens junction organization
positive regulation of axon extension

Function(s)

calcium ion binding