Mm00090804_cn

• Gene Symbol: Fbxw7
• Assay Reference Genome Location: Chr.3:84967496 on build GRCm38
• Cytoband: 3F1

Target Gene Details

• Entrez Gene ID: 50754
• Gene Name: F-box and WD-40 domain protein 7
• Gene Aliases: 1110001A17Rik, AGO, Cdc4, Fbw7, Fbwd6, Fbx30, Fbxo30, Fbxw6, SEL-10
• Location: Chr.3:84815577-84979198 on Build GRCm38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Fbxw7	NM_001177773.1	8	1301	NP_001171244.1
	NM_001177774.1	7	1210	NP_001171245.1
	NM_080428.3	5	846	NP_536353.2
	AB221593.1	5	688
	AF391192.1	5	846	AAL40928.1
	AF427101.1	5	768	AAL50052.1
	BC085184.1	8	1400
	BC131648.1	5	710

More Information

• Set Membership: Intragenic, Exonic

Gene Ontology Categories:

Process(es)

vasculogenesis
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
sister chromatid cohesion
Notch signaling pathway
protein ubiquitination
lung development
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
positive regulation of protein ubiquitination
negative regulation of DNA endoreduplication
cellular response to UV
positive regulation of epidermal growth factor-activated receptor activity
protein stabilization
positive regulation of ubiquitin-protein transferase activity
positive regulation of ERK1 and ERK2 cascade
positive regulation of proteasomal protein catabolic process
regulation of mitophagy
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
positive regulation of protein targeting to mitochondrion
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

transcription factor activity, sequence-specific DNA binding
protein binding
cyclin binding
protein binding, bridging
ubiquitin protein ligase binding
identical protein binding
ubiquitin-protein transferase activator activity