Mm00099330_cn

• Gene Symbol: Rapgef2
• Assay Reference Genome Location: Chr.3:79082596 on build GRCm38
• Cytoband: 3E3

Target Gene Details

• Entrez Gene ID: 76089
• Gene Name: Rap guanine nucleotide exchange factor (GEF) 2
• Gene Aliases: 5830453M24Rik, CNRasGEF, Pdzgef1, RA-GEF-1, mKIAA0313, nRapGEP
• Location: Chr.3:79062516-79287244 on Build GRCm38
• Assay Gene Location: Overlaps Intron 17 - Exon 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Rapgef2	NM_001099624.2			NP_001093094.2
	AB093228.1			BAC41412.1
	AK147368.1
	BC067056.1			AAH67056.1

More Information

• Set Membership: Intragenic, Non-exonic

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

blood vessel development
neuron migration
signal transduction
G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
small GTPase mediated signal transduction
multicellular organism development
nervous system development
negative regulation of cell proliferation
positive regulation of neuron projection development
cAMP-mediated signaling
ventricular system development
forebrain neuron development
microvillus assembly
cell differentiation
neuron projection development
brain-derived neurotrophic factor receptor signaling pathway
positive regulation of protein binding
Rap protein signal transduction
nerve growth factor signaling pathway
positive regulation of GTPase activity
positive regulation of cAMP-mediated signaling
positive regulation of protein kinase activity
negative regulation of melanin biosynthetic process
regulation of synaptic plasticity
negative regulation of dendrite morphogenesis
establishment of endothelial barrier
positive regulation of ERK1 and ERK2 cascade
cellular response to cAMP
cellular response to cGMP
adenylate cyclase-activating adrenergic receptor signaling pathway
protein localization to plasma membrane
establishment of endothelial intestinal barrier
regulation of cell junction assembly
cellular response to nerve growth factor stimulus
positive regulation of cAMP-dependent protein kinase activity
positive regulation of dendritic cell apoptotic process
positive regulation of vasculogenesis
positive regulation of neuron migration

Function(s)

guanyl-nucleotide exchange factor activity
Ras guanyl-nucleotide exchange factor activity
GTPase activator activity
Rap guanyl-nucleotide exchange factor activity
protein kinase binding
PDZ domain binding
beta-1 adrenergic receptor binding
WW domain binding
phosphatidic acid binding