Mm00197266_cn

• Gene Symbol: Ptpn6
• Assay Reference Genome Location: Chr.6:124720808 on build GRCm38
• Cytoband: 6F2

Target Gene Details

• Entrez Gene ID: 15170
• Gene Name: protein tyrosine phosphatase, non-receptor type 6
• Gene Aliases: 70Z-SHP, Hcph, PTPTY-42, Ptp1C, SH-PTP1, SHP-1, hcp, me
• Location: Chr.6:124720707-124738709 on Build GRCm38
• Assay Gene Location: Within Exon 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Ptpn6	NM_001077705.2	16	2120	NP_001071173.1
	NM_013545.3	16	2118	NP_038573.2
	AK132509.1	15	2208	BAE21210.1
	AK150509.1	16	2025	BAE29622.1
	AK151077.1	16	2039	BAE30092.1
	AK151623.1	16	2042
	AK159686.1	16	2078
	AK159833.1	16	2071
	AK167923.1	16	2072
	AK169804.1	16	2120	BAE41378.1
	BC012660.1	16	2063	AAH12660.1
	M68902.1	16	2070	AAA37796.1
	M90389.1	16	2020	AAA40007.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

hematopoietic progenitor cell differentiation
negative regulation of humoral immune response mediated by circulating immunoglobulin
protein dephosphorylation
signal transduction
cell proliferation
positive regulation of cell proliferation
positive regulation of phosphatidylinositol 3-kinase signaling
dephosphorylation
peptidyl-tyrosine phosphorylation
cytokine-mediated signaling pathway
cell differentiation
platelet formation
abortive mitotic cell cycle
positive regulation of cell adhesion mediated by integrin
peptidyl-tyrosine dephosphorylation
intracellular signal transduction
megakaryocyte development
negative regulation of T cell proliferation
natural killer cell mediated cytotoxicity
negative regulation of MAP kinase activity
negative regulation of MAPK cascade
regulation of B cell differentiation
negative regulation of peptidyl-tyrosine phosphorylation
B cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of T cell receptor signaling pathway
regulation of release of sequestered calcium ion into cytosol
regulation of ERK1 and ERK2 cascade
platelet aggregation
regulation of G1/S transition of mitotic cell cycle

Function(s)

phosphotyrosine binding
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
protein binding
hydrolase activity
phosphatase activity
SH3 domain binding
protein kinase binding
SH2 domain binding
natural killer cell lectin-like receptor binding