Mm00217218_cn

• Gene Symbol: Irf3
• Assay Reference Genome Location: Chr.7:44998793 on build GRCm38
• Cytoband: 7B3

Target Gene Details

• Entrez Gene ID: 54131
• Gene Name: interferon regulatory factor 3
• Gene Aliases: C920001K05Rik, IRF-3
• Location: Chr.7:44997648-45002848 on Build GRCm38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Irf3	NM_016849.4	2	350	NP_058545.1
	NR_045611.1	2	508
	AK013944.1	2	342
	AK145977.1	2	483	BAE26800.1
	AK146378.1	2	329	BAE27126.1
	AK151750.1	2	330	BAE30660.1
	AK152689.1	2	330	BAE31420.1
	BC050882.1	2	212	AAH50882.1
	BY089035.1	2	352
	EU545481.1	1	81
	U75839.1	2	324	AAB36924.1
	U75840.1	2	207	AAB36925.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
immune system process
transcription, DNA-templated
regulation of transcription, DNA-templated
response to bacterium
lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to exogenous dsRNA
innate immune response
type I interferon biosynthetic process
negative regulation of interferon-beta biosynthetic process
negative regulation of defense response to virus by host
positive regulation of cytokine secretion
defense response to virus
positive regulation of type I interferon-mediated signaling pathway
cellular response to lipopolysaccharide
programmed necrotic cell death

Function(s)

regulatory region DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
identical protein binding
protein homodimerization activity
transcription regulatory region DNA binding