Mm00260614_cn

• Gene Symbol: Nol3
• Assay Reference Genome Location: Chr.8:105276528 on build GRCm38
• Cytoband: 8D3

Target Gene Details

• Entrez Gene ID: 78688
• Gene Name: nucleolar protein 3 (apoptosis repressor with CARD domain)
• Gene Aliases: ARC, B430311C09Rik, MYC, NOP, Nop30
• Location: Chr.8:105275937-105281939 on Build GRCm38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Nol3	NM_030152.4	1	82	NP_084428.1
	AK021023.1			BAB32281.1
	AK053846.1	1	83	BAC35554.1
	AK079536.1	1	114	BAC37674.1
	AY459322.1	1	90	AAR22550.1
	BC027290.1	1	109	AAH27290.1

More Information

• Set Membership: Intragenic, Exonic

Gene Ontology Categories:

Process(es)

response to hypoxia
blood vessel remodeling
response to ischemia
mRNA splice site selection
mRNA processing
regulation of gene expression
cardiac muscle cell apoptotic process
negative regulation of striated muscle cell apoptotic process
negative regulation of cardiac muscle cell apoptotic process
negative regulation of tumor necrosis factor-mediated signaling pathway
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
negative regulation of muscle atrophy
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
response to injury involved in regulation of muscle adaptation
regulation of NF-kappaB import into nucleus
regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
myoblast differentiation
smooth muscle cell proliferation
protein oligomerization
negative regulation of cytosolic calcium ion concentration
negative regulation of mitochondrial calcium ion concentration
negative regulation of necrotic cell death
cellular response to hypoxia
negative regulation of release of cytochrome c from mitochondria
intrinsic apoptotic signaling pathway
inhibition of cysteine-type endopeptidase activity
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of mitochondrial membrane permeability involved in apoptotic process
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of death-inducing signaling complex assembly
negative regulation of hydrogen peroxide-induced cell death
negative regulation of protein targeting to mitochondrion
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
inhibition of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

receptor binding
death receptor binding
calcium ion binding
protein binding
kinase binding
phosphatase binding
death effector domain binding
identical protein binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
metal ion binding
caspase binding