Mm00325556_cn

• Gene Symbol: Alox12
• Assay Reference Genome Location: Chr.11:70247027 on build GRCm38
• Cytoband: 11B3

Target Gene Details

• Entrez Gene ID: 11684
• Gene Name: arachidonate 12-lipoxygenase
• Gene Aliases: 9930022G08Rik, Alox12p, P-12LO
• Location: Chr.11:70241455-70255386 on Build GRCm38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Alox12	NM_007440.4	10	1355	NP_031466.2
	AK036898.1	10	1353	BAC29629.1
	AK036960.1	10	1311
	AK087724.1	10	1356	BAC39981.1
	AK172216.1	10	1353	BAE42887.1
	AK172488.1	10	1356	BAE43031.1
	BC152329.1	10	1360
	BC152403.1	10	1360
	S80446.1	10	1367	AAB36013.1
	U04334.1	10	1286	AAA20659.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

lipid metabolic process
fatty acid metabolic process
movement of cell or subcellular component
positive regulation of cell proliferation
positive regulation of endothelial cell migration
positive regulation of gene expression
negative regulation of muscle cell apoptotic process
positive regulation of cell death
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
positive regulation of cell growth
positive regulation of cell migration
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of endothelial cell differentiation
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of vasodilation
positive regulation of smooth muscle cell proliferation
hepoxilin biosynthetic process
positive regulation of mitochondrial depolarization
oxidation-reduction process
establishment of skin barrier
negative regulation of platelet aggregation
lipoxin A4 biosynthetic process
lipoxin B4 biosynthetic process

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
juvenile hormone epoxide hydrolase activity
linoleate 13S-lipoxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
hydrolase activity
epoxide hydrolase B activity
phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity
epoxide hydrolase A activity
phenanthrene-3,4-epoxide hydrolase activity
phenanthrene-1,2-epoxide hydrolase activity
phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity
phenanthrene-epoxide hydrolase activity
phenanthrene-9,10-epoxide hydrolase activity
pyrene-4,5-epoxide hydrolase activity
metal ion binding
dioxygenase activity