Mm00453891_cn

• Gene Symbol: Pak2
• Assay Reference Genome Location: Chr.16:32052234 on build GRCm38
• Cytoband: 16B2

Target Gene Details

• Entrez Gene ID: 224105
• Gene Name: p21 protein (Cdc42/Rac)-activated kinase 2
• Gene Aliases: 5330420P17Rik, A130002K10Rik, AI836325, D16Ertd269e, PAK-2, mKIAA4182
• Location: Chr.16:32016290-32079342 on Build GRCm38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Pak2	NM_177326.3	2	405	NP_796300.1
	AK037275.1	2	406
	AK190087.1	1	55
	AY167030.1	1	131	AAN65624.1
	BC086650.1	2	336	AAH86650.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

protein phosphorylation
apoptotic process
Rho protein signal transduction
regulation of mitotic cell cycle
metabolic process
phosphorylation
cell migration
peptidyl-serine phosphorylation
signal transduction by protein phosphorylation
actin cytoskeleton organization
stress-activated protein kinase signaling cascade
activation of protein kinase activity
regulation of growth
negative regulation of apoptotic process
regulation of MAPK cascade
protein autophosphorylation
positive regulation of peptidyl-tyrosine phosphorylation
dendritic spine development
positive regulation of protein tyrosine kinase activity
cellular response to organic cyclic compound
positive regulation of extrinsic apoptotic signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Function(s)

nucleotide binding
catalytic activity
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
protein tyrosine kinase activator activity
identical protein binding
Rac GTPase binding