Mm00458811_cn

• Gene Symbol: Cdkn1a
• Assay Reference Genome Location: Chr.17:29093812 on build GRCm38
• Cytoband: 17A3.3

Target Gene Details

• Entrez Gene ID: 12575
• Gene Name: cyclin-dependent kinase inhibitor 1A (P21)
• Gene Aliases: CAP20, CDKI, CIP1, Cdkn1, P21, SDI1, Waf1, mda6, p21Cip1, p21WAF
• Location: Chr.17:29090986-29100722 on Build GRCm38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Cdkn1a	NM_001111099.1			NP_001104569.1
	NM_007669.4			NP_031695.1
	AK007630.1			BAB25148.1
	AK089093.1			BAC40747.1
	AK139306.1			BAE23949.1
	AK149910.1			BAE29160.1
	AK170467.1			BAE41815.1
	BC002043.1			AAH02043.1
	BY206886.1
	U24173.1			AAC52220.1

More Information

• Set Membership: Intragenic, Non-exonic

Panther Classification:

Molecular Function -

kinase inhibitor

Gene Ontology Categories:

Process(es)

regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
protein phosphorylation
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
cell cycle
cell cycle arrest
regulation of mitotic cell cycle
negative regulation of cell proliferation
response to UV
negative regulation of gene expression
negative regulation of cell growth
positive regulation of B cell proliferation
cellular response to extracellular stimulus
regulation of protein import into nucleus, translocation
negative regulation of phosphorylation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of apoptotic process
positive regulation of programmed cell death
negative regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of protein kinase activity
positive regulation of fibroblast proliferation
regulation of cell cycle
cellular response to ionizing radiation
cellular response to UV-B
mitotic cell cycle arrest
signal transduction by p53 class mediator
cellular senescence
negative regulation of G1/S transition of mitotic cell cycle
regulation of DNA biosynthetic process
positive regulation of reactive oxygen species metabolic process

Function(s)

protein kinase inhibitor activity
cyclin-dependent protein serine/threonine kinase inhibitor activity
protein binding
cyclin-dependent protein kinase activating kinase activity
cyclin binding
ubiquitin protein ligase binding
protein complex binding
metal ion binding