Mm00469941_cn

• Gene Symbol: Msh2
• Assay Reference Genome Location: Chr.17:87712719 on build GRCm38
• Cytoband: 17E4

Target Gene Details

• Entrez Gene ID: 17685
• Gene Name: mutS homolog 2 (E. coli)
• Gene Aliases: AI788990
• Location: Chr.17:87672557-87723713 on Build GRCm38
• Assay Gene Location: Overlaps Exon 11 - Intron 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Msh2	NM_008628.2			NP_032654.1
	AK157842.1			BAE34223.1
	AK166179.1
	BC047117.1			AAH47117.1
	BC050897.1			AAH50897.1
	U21011.1			AAA75027.1
	X81143.1			CAA57049.1

More Information

• Set Membership: Intragenic, Non-exonic

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

meiotic mismatch repair
in utero embryonic development
somatic recombination of immunoglobulin genes involved in immune response
oxidative phosphorylation
DNA repair
mismatch repair
postreplication repair
double-strand break repair
meiotic gene conversion
cellular response to DNA damage stimulus
cell cycle
cell cycle arrest
reciprocal meiotic recombination
germ cell development
determination of adult lifespan
male gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
response to X-ray
response to UV-B
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
B cell mediated immunity
B cell differentiation
intra-S DNA damage checkpoint
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of neuron apoptotic process
maintenance of DNA repeat elements
negative regulation of reciprocal meiotic recombination
isotype switching
negative regulation of DNA recombination
positive regulation of helicase activity

Function(s)

nucleotide binding
magnesium ion binding
four-way junction DNA binding
Y-form DNA binding
heteroduplex DNA loop binding
double-strand/single-strand DNA junction binding
DNA binding
damaged DNA binding
double-stranded DNA binding
single-stranded DNA binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
ATPase activity
centromeric DNA binding
enzyme binding
protein kinase binding
mismatched DNA binding
guanine/thymine mispair binding
single base insertion or deletion binding
dinucleotide insertion or deletion binding
single guanine insertion binding
single thymine insertion binding
dinucleotide repeat insertion binding
oxidized purine DNA binding
MutLalpha complex binding
protein homodimerization activity
ADP binding