Mm00526189_cn

• Gene Symbol: Hdac6
• Assay Reference Genome Location: Chr.X:7938436 on build GRCm38
• Cytoband: XA1.1

Target Gene Details

• Entrez Gene ID: 15185
• Gene Name: histone deacetylase 6
• Gene Aliases: Hd6, Hdac5, Sfc6, mHDA2
• Location: Chr.X:7930120-7947889 on Build GRCm38
• Assay Gene Location: Within Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Hdac6	NM_001130416.1	15	1473	NP_001123888.1
	NM_010413.3	15	1548	NP_034543.3
	AF006603.2	14	1233	AAD09835.2
	AK148092.1	15	1394
	AK148144.1	15	1364	BAE28372.1
	AK154099.1	15	1412	BAE32376.1
	AK155545.1	13	2446
	AK155546.1	15	1412
	AK183013.1
	BC041105.1	15	1405	AAH41105.1

More Information

• Set Membership: Intragenic, Exonic

Gene Ontology Categories:

Process(es)

protein polyubiquitination
transcription, DNA-templated
regulation of transcription, DNA-templated
protein deacetylation
ubiquitin-dependent protein catabolic process
misfolded or incompletely synthesized protein catabolic process
intracellular protein transport
negative regulation of microtubule depolymerization
response to toxic substance
positive regulation of signal transduction
response to organic substance
regulation of receptor activity
positive regulation of epithelial cell migration
positive regulation of receptor biosynthetic process
macroautophagy
chromatin modification
histone deacetylation
lysosome localization
peptidyl-lysine deacetylation
cellular response to topologically incorrect protein
regulation of gene expression, epigenetic
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
protein complex disassembly
negative regulation of protein complex disassembly
regulation of fat cell differentiation
negative regulation of proteolysis
mitochondrion localization
response to misfolded protein
regulation of establishment of protein localization
cellular response to hydrogen peroxide
aggresome assembly
polyubiquitinated misfolded protein transport
Hsp90 deacetylation
response to growth factor
cellular response to misfolded protein
positive regulation of chaperone-mediated protein complex assembly
tubulin deacetylation
mitophagy in response to mitochondrial depolarization
positive regulation of hydrogen peroxide-mediated programmed cell death

Function(s)

core promoter binding
actin binding
histone deacetylase activity
protein binding
beta-catenin binding
microtubule binding
zinc ion binding
hydrolase activity
histone deacetylase activity (H3-K14 specific)
polyubiquitin binding
ubiquitin protein ligase binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
histone deacetylase activity (H3-K9 specific)
histone deacetylase activity (H4-K16 specific)
histone deacetylase binding
tubulin deacetylase activity
alpha-tubulin binding
ubiquitin binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
tau protein binding
beta-tubulin binding
misfolded protein binding
Hsp90 protein binding
dynein complex binding
NAD-dependent histone deacetylase activity (H3-K18 specific)