Mm00588281_cn

• Gene Symbol: Mdm2
• Assay Reference Genome Location: Chr.10:117690466 on build GRCm38
• Cytoband: 10D2

Target Gene Details

• Entrez Gene ID: 17246
• Gene Name: transformed mouse 3T3 cell double minute 2
• Gene Aliases: 1700007J15Rik, AA415488, Mdm-2
• Location: Chr.10:117688875-117710770 on Build GRCm38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Mdm2	NM_001288586.1	11	1423	NP_001275515.1
	NM_010786.4	12	1508	NP_034916.1
	AK004719.1	12	1467	BAB23502.1
	AK004881.1	10	2650
	AK088638.1	12	1438	BAC40470.1
	AK150530.1	10	1199
	AK152685.1	10	1199
	AK160069.1	11	1299	BAE35604.1
	AK168690.1	12	1491
	BC050902.1	12	1424	AAH50902.1
	BC092270.1	12	1455	AAH92270.1
	U47934.1	10	1214	AAB09031.1
	X58876.1	12	1415	CAA41684.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
traversing start control point of mitotic cell cycle
positive regulation of gene expression
negative regulation of gene expression
negative regulation of protein processing
protein ubiquitination
peptidyl-lysine modification
protein catabolic process
protein destabilization
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein localization to nucleus
regulation of protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of DNA damage response, signal transduction by p53 class mediator
establishment of protein localization
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
positive regulation of protein export from nucleus
negative regulation of cell cycle arrest
negative regulation of signal transduction by p53 class mediator

Function(s)

p53 binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
enzyme binding
ubiquitin protein ligase binding
identical protein binding
peroxisome proliferator activated receptor binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
scaffold protein binding