Mm00621853_cn

• Gene Symbol: Slc8a1
• Assay Reference Genome Location: Chr.17:81383741 on build GRCm38
• Cytoband: 17E3

Target Gene Details

• Entrez Gene ID: 20541
• Gene Name: solute carrier family 8 (sodium/calcium exchanger), member 1
• Gene Aliases: AI852629, AV344025, D930008O12Rik, Ncx1
• Location: Chr.17:81373105-81738387 on Build GRCm38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Slc8a1	NM_001112798.2	9	7937	NP_001106269.1
	NM_001286684.1	12	5211	NP_001273613.1
	NM_011406.3	11	7973	NP_035536.2
	NR_104580.1	9	7972
	AK052989.1	1	3236
	BB660129.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

secondary carrier transporter

Gene Ontology Categories:

Process(es)

response to hypoxia
embryonic placenta development
regulation of the force of heart contraction
regulation of heart rate
regulation of sodium ion transport
heart morphogenesis
transport
ion transport
sodium ion transport
calcium ion transport
cellular calcium ion homeostasis
cellular sodium ion homeostasis
cell communication
positive regulation of cytosolic calcium ion concentration
post-embryonic development
positive regulation of fibroblast migration
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
vascular smooth muscle contraction
positive regulation of bone mineralization
response to ATP
cellular response to reactive oxygen species
embryonic heart tube development
sodium ion transmembrane transport
response to muscle stretch
relaxation of smooth muscle
muscle fiber development
negative regulation of cytosolic calcium ion concentration
regulation of calcium ion transport
cardiac muscle cell development
calcium ion homeostasis
transmembrane transport
cardiac muscle contraction
calcium ion transport into cytosol
calcium ion import
calcium ion transmembrane transport
cellular response to caffeine
cellular response to cAMP
sodium ion export
regulation of cardiac muscle cell membrane potential
cell communication by electrical coupling involved in cardiac conduction
sodium ion import
positive regulation of the force of heart contraction
calcium ion export

Function(s)

calcium:sodium antiporter activity
protein binding
calmodulin binding
cytoskeletal protein binding
antiporter activity
ankyrin binding
ion channel binding
metal ion binding
calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential