Mm00626724_cn

• Gene Symbol: Pdgfrb
• Assay Reference Genome Location: Chr.18:61061309 on build GRCm38
• Cytoband: 18E1

Target Gene Details

• Entrez Gene ID: 18596
• Gene Name: platelet derived growth factor receptor, beta polypeptide
• Gene Aliases: AI528809, CD140b, PDGFR-1, Pdgfr
• Location: Chr.18:61045150-61085068 on Build GRCm38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Pdgfrb	NM_001146268.1	3	574	NP_001139740.1
	NM_008809.2	3	574	NP_032835.2
	AK134785.1	4	596	BAE22283.1
	AK143247.1	3	554
	BC055311.1	3	586	AAH55311.1
	BY753644.1	3	577
	X04367.1	3	283	CAA27882.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

in utero embryonic development
kidney development
tissue homeostasis
glycosaminoglycan biosynthetic process
protein phosphorylation
nitrogen compound metabolic process
chemotaxis
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
positive regulation of cell proliferation
positive regulation of phospholipase C activity
positive regulation of phosphatidylinositol 3-kinase signaling
positive regulation of smooth muscle cell migration
phosphorylation
cell migration
peptidyl-tyrosine phosphorylation
hemopoiesis
adrenal gland development
positive regulation of cell migration
positive regulation of phosphoprotein phosphatase activity
regulation of actin cytoskeleton organization
positive regulation of collagen biosynthetic process
cell migration involved in vasculogenesis
intracellular signal transduction
metanephric mesenchymal cell migration
platelet-derived growth factor receptor-beta signaling pathway
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
aorta morphogenesis
cellular response to platelet-derived growth factor stimulus
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
negative regulation of apoptotic process
positive regulation of MAP kinase activity
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of mitotic nuclear division
phosphatidylinositol metabolic process
protein autophosphorylation
platelet-derived growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
positive regulation of smooth muscle cell proliferation
skeletal system morphogenesis
smooth muscle tissue development
regulation of peptidyl-tyrosine phosphorylation
positive regulation of chemotaxis
cardiac myofibril assembly
cell chemotaxis
cardiac vascular smooth muscle cell differentiation
cell migration involved in coronary angiogenesis
retina vasculature development in camera-type eye
positive regulation of ERK1 and ERK2 cascade
smooth muscle cell chemotaxis
metanephric glomerular mesangial cell proliferation involved in metanephros development
metanephric glomerular capillary formation
positive regulation of calcium ion import
positive regulation of reactive oxygen species metabolic process
positive regulation of DNA biosynthetic process

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer activity
platelet-derived growth factor-activated receptor activity
platelet-derived growth factor beta-receptor activity
receptor binding
platelet-derived growth factor receptor binding
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
vascular endothelial growth factor binding
phosphatidylinositol 3-kinase binding
platelet-derived growth factor binding