Mm00645242_cn

• Gene Symbol: Il6ra
• Assay Reference Genome Location: Chr.3:89887120 on build GRCm38
• Cytoband: 3F1

Target Gene Details

• Entrez Gene ID: 16194
• Gene Name: interleukin 6 receptor, alpha
• Gene Aliases: CD126, IL-6R, Il6r
• Location: Chr.3:89868829-89913492 on Build GRCm38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Il6ra	NM_010559.2	4	656	NP_034689.2
	AK046337.1	4	655
	AK082270.1	4	656
	AK141197.1	4	691	BAE24580.1
	X51975.1	4	547	CAA36237.1
	X53802.1	4	656	CAA37810.1

More Information

• Set Membership: Intragenic, Exonic

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

positive regulation of cell proliferation
positive regulation of activation of Janus kinase activity
cell growth
cytokine-mediated signaling pathway
endocrine pancreas development
positive regulation of chemokine production
positive regulation of interleukin-6 production
negative regulation of collagen biosynthetic process
response to cytokine
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of MAPK cascade
positive regulation of JAK-STAT cascade
positive regulation of smooth muscle cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
interleukin-6-mediated signaling pathway
ciliary neurotrophic factor-mediated signaling pathway

Function(s)

cytokine receptor activity
ciliary neurotrophic factor receptor activity
interleukin-6 receptor activity
interleukin-6 receptor binding
enzyme binding
interleukin-6 binding
protein homodimerization activity
ciliary neurotrophic factor binding