Mm00733935_cn

• Gene Symbol: Bbc3
• Assay Reference Genome Location: Chr.7:16311744 on build GRCm38
• Cytoband: 7A2

Target Gene Details

• Entrez Gene ID: 170770
• Gene Name: BCL2 binding component 3
• Gene Aliases: PUMA, PUMA/JFY1
• Location: Chr.7:16308321-16318334 on Build GRCm38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Bbc3	NM_133234.2			NP_573497.1
	AF332560.1			AAK31317.1
	BC044782.2			AAH44782.1
	BC060370.1			AAH60370.1
	BC147261.1
	BC147262.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, Validated

Gene Ontology Categories:

Process(es)

release of cytochrome c from mitochondria
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
determination of adult lifespan
negative regulation of cell growth
positive regulation of protein homooligomerization
negative regulation of endoplasmic reticulum calcium ion concentration
response to endoplasmic reticulum stress
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
negative regulation of growth
release of sequestered calcium ion into cytosol
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
positive regulation of thymocyte apoptotic process
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
apoptotic signaling pathway
execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
toxin transport
positive regulation of cysteine-type endopeptidase activity
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding