Bt03215936_m1 Best Coverage

• Gene Symbol: PSEN1
• Gene Name: presenilin 1
• Gene Aliases: -
• Chromosome Location: Chr.10: 84619595 - 84686880 on Build ARS-UCD1.2
• Species: Bovine
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PSEN1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_174721.2	NP_777146.1	4 - 5	558		95
GenBank mRNA	AF038936.1	-	4 - 5	558		95
	BC151458.1	-	6 - 7	759		95

More Information

• Set Membership: Amplicon length between 86 and 100, Mammalian Gene Collection, Recommended Assay, Bos taurus, Inventoried, Probe spans exons

Panther Classification:

Molecular Function -

aspartic protease

Gene Ontology Categories:

Process(es)

autophagosome assembly
negative regulation of transcription from RNA polymerase II promoter
activation of MAPKK activity
blood vessel development
cell fate specification
somitogenesis
neuron migration
positive regulation of receptor recycling
heart looping
positive regulation of L-glutamate transport
hematopoietic progenitor cell differentiation
astrocyte activation involved in immune response
T cell activation involved in immune response
protein glycosylation
membrane protein ectodomain proteolysis
mitochondrial transport
cellular response to DNA damage stimulus
response to oxidative stress
negative regulation of epidermal growth factor-activated receptor activity
Notch signaling pathway
memory
post-embryonic development
regulation of neuron projection development
protein transport
choline transport
synaptic vesicle targeting
protein processing
cerebral cortex cell migration
Cajal-Retzius cell differentiation
dorsal/ventral neural tube patterning
embryonic limb morphogenesis
positive regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
endoplasmic reticulum calcium ion homeostasis
beta-amyloid formation
intracellular signal transduction
positive regulation of protein import into nucleus
positive regulation of tumor necrosis factor biosynthetic process
amyloid precursor protein metabolic process
myeloid dendritic cell differentiation
positive regulation of apoptotic process
positive regulation of catalytic activity
skin morphogenesis
positive regulation of glycolytic process
positive regulation of transcription, DNA-templated
regulation of synaptic plasticity
thymus development
neuron development
skeletal system morphogenesis
brain morphogenesis
epithelial cell proliferation
negative regulation of axonogenesis
synapse organization
positive regulation of coagulation
T cell receptor signaling pathway
neuron apoptotic process
negative regulation of ubiquitin-protein transferase activity
regulation of synaptic transmission, glutamatergic
regulation of resting membrane potential
regulation of canonical Wnt signaling pathway
positive regulation of dendritic spine development
calcium ion transmembrane transport
modulation of age-related behavioral decline
cell-cell adhesion
cellular response to beta-amyloid
negative regulation of core promoter binding
positive regulation of amyloid fibril formation
neuron projection maintenance
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic signaling pathway

Function(s)

calcium channel activity
PDZ domain binding
aspartic endopeptidase activity, intramembrane cleaving