Cf02690631_m1 Best Coverage

• Gene Symbol: PTEN
• Gene Name: phosphatase and tensin homolog
• Gene Aliases: MMAC1
• Chromosome Location: Chr.26: 37853148 - 37913176 on Build CanFam3.1
• Species: Dog
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PTEN
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001003192.1	NP_001003192.1	6 - 7	915		83
GenBank mRNA	U92435.1	-	6 - 7	915		83

More Information

Additional Information:

This assay maps with 100% identity to the human homologue, and the human gene symbol was added in the Alias field to assist with searches.

• Set Membership: Amplicon length between 71 and 85, 3' Most, Recommended Assay, Canis familiaris, Inventoried, Probe spans exons

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

angiogenesis
regulation of B cell apoptotic process
protein dephosphorylation
apoptotic process
neuron-neuron synaptic transmission
central nervous system development
heart development
learning or memory
positive regulation of cell proliferation
negative regulation of cell proliferation
negative regulation of epithelial to mesenchymal transition
regulation of neuron projection development
cell migration
dentate gyrus development
central nervous system neuron axonogenesis
negative regulation of cell migration
adult behavior
negative regulation of myelination
regulation of protein stability
regulation of synaptic transmission, GABAergic
central nervous system myelin maintenance
regulation of myeloid cell apoptotic process
negative regulation of peptidyl-serine phosphorylation
multicellular organismal response to stress
social behavior
peptidyl-tyrosine dephosphorylation
maternal behavior
negative regulation of apoptotic process
protein kinase B signaling
endothelial cell migration
locomotor rhythm
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of cell size
inositol phosphate dephosphorylation
phosphatidylinositol dephosphorylation
negative regulation of axon regeneration
cardiac muscle tissue development
forebrain morphogenesis
negative regulation of epithelial cell proliferation
negative regulation of axonogenesis
protein stabilization
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of keratinocyte migration
negative regulation of focal adhesion assembly
negative regulation of protein kinase B signaling
rhythmic synaptic transmission
negative regulation of cardiac muscle cell proliferation
canonical Wnt signaling pathway
synapse maturation
prepulse inhibition
male mating behavior
long-term synaptic potentiation
prostate gland growth
dendritic spine morphogenesis
negative regulation of dendritic spine morphogenesis
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
cellular response to electrical stimulus
cellular response to hypoxia
negative regulation of ribosome biogenesis
negative regulation of cell aging
negative regulation of excitatory postsynaptic potential
presynaptic membrane assembly
postsynaptic density assembly
negative regulation of wound healing, spreading of epidermal cells
positive regulation of TRAIL-activated apoptotic signaling pathway
positive regulation of ubiquitin protein ligase activity
negative regulation of vascular smooth muscle cell proliferation
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of G1/S transition of mitotic cell cycle
positive regulation of excitatory postsynaptic potential
negative regulation of synaptic vesicle clustering

Function(s)

phosphatidylinositol-3-phosphatase activity
protein serine/threonine phosphatase activity
protein tyrosine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
anaphase-promoting complex binding
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
protein kinase binding
PDZ domain binding
identical protein binding
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
ubiquitin-specific protease binding