Cf02717353_g1 Best Coverage

• Gene Symbol: TLR9
• Gene Name: toll like receptor 9
• Gene Aliases: -
• Chromosome Location: Chr.20: 37529322 - 37547117 on Build CanFam3.1
• Species: Dog
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TLR9
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001002998.1	NP_001002998.1	3	749		136
	XM_014121722.2	XP_013977197.1	2	776		136
	XM_014121724.2	XP_013977199.1	9	1619		136
GenBank mRNA	AB104899.3	-	3	749		136
	AY859723.1	-	2	687		136

More Information

Additional Information:

This assay maps with 100% identity to the human homologue, and the human gene symbol was added in the Alias field to assist with searches.

• Set Membership: Amplicon length greater than or equal to 101, 3' Most, Detect Genomic DNA, Recommended Assay, Canis familiaris, Both primers and probe map within a single exon

Gene Ontology Categories:

Process(es)

activation of innate immune response
response to molecule of bacterial origin
positive regulation of immunoglobulin production
regulation of dendritic cell cytokine production
MyD88-dependent toll-like receptor signaling pathway
inflammatory response
maintenance of gastrointestinal epithelium
positive regulation of B cell proliferation
negative regulation of interleukin-6 production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of interferon-gamma production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
positive regulation of interleukin-18 production
positive regulation of tumor necrosis factor production
toll-like receptor 9 signaling pathway
regulation of toll-like receptor 9 signaling pathway
positive regulation of toll-like receptor 9 signaling pathway
positive regulation of MAPK cascade
innate immune response
regulation of B cell differentiation
positive regulation of transcription from RNA polymerase II promoter
regulation of cytokine secretion
positive regulation of inflammatory response
positive regulation of B cell activation
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to chloroquine

Function(s)

transmembrane signaling receptor activity
siRNA binding
pattern recognition receptor activity
protein homodimerization activity
unmethylated CpG binding