Dm01804009_g1

• Gene Symbol: Utx
• Gene Name: Utx histone demethylase
• Gene Aliases: CG5640, Dmel\CG5640, Dmel_CG5640, UTX, anon-31BCa, dUTX, dUtx, utx
• Chromosome Location: Chr.2L: 10272325 - 10278811 on Build Release_6_plus_ISO1_MT
• Species: Drosophila melanogaster
• Species Specific ID (Flybase ID): FBgn0260749

Assay Details

Gene Symbol: Utx
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001201844.1	NP_001188773.1	13 - 14	3188		140
	NM_001273390.1	NP_001260319.1	11 - 12	2919		140
	NM_135524.4	NP_609368.3	13 - 14	3206		140
	NM_164907.4	NP_723550.2	11 - 12	2741		140
	NM_164908.4	NP_723551.2	11 - 12	2729		140
GenBank mRNA	AY129437.1	-	13 - 14	3271		140
	BT010089.1	-	13 - 14	3206		140

More Information

• Set Membership: Amplicon length greater than or equal to 101, Drosophila melanogaster

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

negative regulation of cell proliferation
positive regulation of autophagy
histone demethylation
ecdysone-mediated induction of salivary gland cell autophagic cell death
wound healing
sex comb development
positive regulation of transcription, DNA-templated
histone H3-K4 methylation
negative regulation of histone H3-K27 methylation
cellular response to ecdysone
cellular response to gamma radiation
histone H3-K27 demethylation
negative regulation of histone H3-K27 trimethylation
regulation of transcription from RNA polymerase II promoter in response to DNA damage

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin binding
chromatin DNA binding
histone demethylase activity
nuclear hormone receptor binding
sequence-specific DNA binding
histone demethylase activity (H3-K27 specific)
promoter-specific chromatin binding