Dm01816286_g1

• Gene Symbol: Dark
• Gene Name: Death-associated APAF1-related killer
• Gene Aliases: APAF-1, APAF1, ARK, Apaf, Apaf-1, Apaf1, Ark, CG6829, D-Apaf-1, DARK, Dapaf-1, Dapaf-1/HAC-1, Dark/Apaf-I, Dark/Dapaf-1/HAC1, Dark/Hac-1/dApaf-1, Dark/Hac-1/dApaf1, Dmel\CG6829, Dmel_CG6829, Hac-1, Hac-1/Dark, Hac1, T1, anon-53Fa, apaf-1, apaf1, arc, ark, dAPAF-1, dApaf-1, dApaf-1/DARK/HAC-1, dApaf1, dArk, dapaf, dapaf-1, dapaf-1L, dapaf-1S, dark, dark/dapaf-1/hac-1, dark/hac-1/dapaf-1, hac-1, hac1, l(2)SH0173
• Chromosome Location: Chr.2R: 17020027 - 17026703 on Build Release_6_plus_ISO1_MT
• Species: Drosophila melanogaster
• Species Specific ID (Flybase ID): FBgn0263864

Assay Details

Gene Symbol: Dark
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_166207.3	NP_725637.1	8 - 9	3599		127
	NM_166208.3	NP_725638.1	7 - 8	3658		127
GenBank mRNA	AB027531.1	-	8 - 9	3561		127
	AF162659.1	-	8 - 9	3450		127
	AF196306.2	-	7 - 8	3384		127
	BT150397.1	-	8 - 9	3582		127

More Information

• Set Membership: Amplicon length greater than or equal to 101, Drosophila melanogaster

Gene Ontology Categories:

Process(es)

negative regulation of humoral immune response
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
sperm individualization
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
response to gamma radiation
programmed cell death
central nervous system formation
chaeta development
S-adenosylmethionine cycle
positive regulation of glial cell apoptotic process
melanization defense response
salivary gland histolysis
salivary gland cell autophagic cell death
response to starvation
positive regulation of apoptotic process
positive regulation of compound eye retinal cell programmed cell death
dendrite morphogenesis
neuron cellular homeostasis
triglyceride homeostasis
sarcosine catabolic process

Function(s)

ATP binding
cysteine-type endopeptidase activator activity involved in apoptotic process
ADP binding
CARD domain binding
cysteine-type endopeptidase activity involved in apoptotic signaling pathway