Hs00174854_m1

• Gene Symbol: AGT
• Gene Name: angiotensinogen
• Gene Aliases: ANHU, SERPINA8
• Chromosome Location: Chr.1: 230702523 - 230714590 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: AGT
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000029.3	NP_000020.1	1 - 2	508		71
GenBank mRNA	AK222798.1	-	1 - 2	39		71
	AK222815.1	-	1 - 2	40		71
	AK293507.1	-	1 - 2	39		71
	AK303755.1	-	1 - 2	38		71
	AK307978.1	-	1 - 2	38		71
	AK312291.1	-	1 - 2	118		71
	AU128714.1	-	1 - 2	214		71
	DC412932.1	-	1 - 2	508		71
	K02215.1	-	1 - 2	39		71

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0100018565.hg.1
This assay targets the same location as HTA transcript cluster(s) TC01006281.hg.1

Additional Information:

This assay is in the 5'UTR region of the AK293507.1,AK303755.1,AK312291.1,K02215.1,NM_000029.3 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Homo sapiens, HUMAN NFAT AND CARDIAC HYPERTROPHY, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene AGT

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

regulation of cell growth
positive regulation of cytokine production
kidney development
blood vessel remodeling
angiotensin maturation
regulation of blood volume by renin-angiotensin
renin-angiotensin regulation of aldosterone production
regulation of renal output by angiotensin
regulation of heart rate
regulation of blood vessel size by renin-angiotensin
renal system process
angiotensin-mediated drinking behavior
positive regulation of extracellular matrix constituent secretion
cellular sodium ion homeostasis
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
phospholipase C-activating G-protein coupled receptor signaling pathway
activation of phospholipase C activity
nitric oxide mediated signal transduction
cell-cell signaling
female pregnancy
aging
regulation of blood pressure
positive regulation of activation of JAK2 kinase activity
positive regulation of endothelial cell migration
positive regulation of cardiac muscle hypertrophy
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol esterification
negative regulation of endopeptidase activity
regulation of norepinephrine secretion
positive regulation of phosphatidylinositol 3-kinase signaling
artery smooth muscle contraction
response to muscle activity involved in regulation of muscle adaptation
negative regulation of angiogenesis
regulation of vasoconstriction
negative regulation of cell growth
positive regulation of cellular protein metabolic process
positive regulation of superoxide anion generation
positive regulation of NAD(P)H oxidase activity
negative regulation of tissue remodeling
low-density lipoprotein particle remodeling
catenin import into nucleus
regulation of renal sodium excretion
positive regulation of renal sodium excretion
regulation of cell proliferation
vasodilation
positive regulation of nitric oxide biosynthetic process
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of blood pressure
positive regulation of transcription, DNA-templated
positive regulation of vasodilation
fibroblast proliferation
positive regulation of fibroblast proliferation
regulation of long-term neuronal synaptic plasticity
smooth muscle cell proliferation
cytokine secretion
positive regulation of inflammatory response
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of NF-kappaB transcription factor activity
negative regulation of neurotrophin TRK receptor signaling pathway
stress-activated MAPK cascade
regulation of calcium ion transport
regulation of transmission of nerve impulse
cell growth involved in cardiac muscle cell development
positive regulation of protein tyrosine kinase activity
ERK1 and ERK2 cascade
uterine smooth muscle contraction
cellular response to mechanical stimulus
positive regulation of branching involved in ureteric bud morphogenesis
regulation of extracellular matrix assembly
positive regulation of gap junction assembly
regulation of cardiac conduction
positive regulation of reactive oxygen species metabolic process
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

serine-type endopeptidase inhibitor activity
hormone activity
protein binding
growth factor activity
type 1 angiotensin receptor binding
type 2 angiotensin receptor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	ENST00000366667.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	ENST00000366667.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	ENST00000366667.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	ENST00000366667.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	ENST00000366667.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	ENST00000366667.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	ENST00000366667.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	ENST00000366667.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	NM_000029.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	NM_000029.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	NM_000029.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	NM_000029.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	NM_000029.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	NM_000029.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	NM_000029.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	NM_000029.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100018565.hg.1	NM_000029.3	Refseq

Array Name	Probe IDs	Targets	Target Type
ABI Human Genome Survey Microarray Version 2.0	148630	-	-