Hs00357734_m1

• Gene Symbol: ELANE
• Gene Name: elastase, neutrophil expressed
• Gene Aliases: ELA2, GE, HLE, HNE, NE, PMN-E, SCN1
• Chromosome Location: Chr.19: 850997 - 856250 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ELANE
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001972.3	NP_001963.1	3 - 4	488		66
	XM_011527775.1	XP_011526077.1	4 - 5	1165		66
	XM_011527776.1	XP_011526078.1	4 - 5	504		66
GenBank mRNA	BC074816.2	-	3 - 4	405	30915534	66
	BC074817.2	-	3 - 4	405	30915320	66
	D00187.1	-	2 - 3	278		66
	J03545.1	-	1 - 2	146		66
	M34379.1	-	3 - 4	406		66
	X05875.1	-	3 - 4	406		66

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1900006493.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protease, Mammalian Gene Collection, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ELANE

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
response to yeast
acute inflammatory response to antigenic stimulus
proteolysis
cellular calcium ion homeostasis
phagocytosis
response to UV
extracellular matrix disassembly
protein catabolic process
response to lipopolysaccharide
defense response to bacterium
positive regulation of MAP kinase activity
negative regulation of growth of symbiont in host
negative regulation of chemokine biosynthetic process
negative regulation of interleukin-8 biosynthetic process
positive regulation of interleukin-8 biosynthetic process
positive regulation of smooth muscle cell proliferation
negative regulation of inflammatory response
positive regulation of immune response
leukocyte migration
negative regulation of chemotaxis
neutrophil mediated killing of fungus

Function(s)

RNA polymerase II transcription corepressor activity
protease binding
endopeptidase activity
serine-type endopeptidase activity
protein binding
heparin binding
peptidase activity
cytokine binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1900144554.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1900144554.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1900144554.hg.1	TC1900006493.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR1900144554.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1900144554.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000263621.1	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000590230.5	Ensembl
Affymetrix Human Clariom D Assay	TC1900006493.hg.1	ENST00000590230.5	Ensembl