Hs00393844_m1

• Gene Symbol: MAVS
• Gene Name: mitochondrial antiviral signaling protein
• Gene Aliases: CARDIF, IPS-1, IPS1, VISA
• Chromosome Location: Chr.20: 3846799 - 3876123 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MAVS
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_020746.4	NP_065797.2	2 - 3	291		69
	NR_037921.1		2 - 3	291		69
GenBank mRNA	AB033097.1	-	1 - 2	197		69
	AB232371.1	-	1 - 2	191		69
	AK023799.1	-	2 - 3	247		69
	AK123956.1	-	2 - 3	252		69
	AK130992.1	-	2 - 3	212		69
	AK296897.1	-	2 - 3	256		69
	BC044952.1	-	2 - 3	225	5751684	69
	BM834250.1	-	2 - 3	255		69
	DB219666.1	-	2 - 3	291		69
	DQ167126.1	-	1 - 2	119		69
	DQ174270.1	-	1 - 2	119		69
	DQ181928.1	-	1 - 2	119		69
	EF467324.1	-	1 - 2	119		69
	KC415005.1	-	1 - 2	119		69

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC20000043.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MAVS

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
activation of innate immune response
positive regulation of defense response to virus by host
signal transduction
negative regulation of type I interferon production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of protein import into nucleus, translocation
RIG-I signaling pathway
defense response to bacterium
positive regulation of transcription factor import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of viral genome replication
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of sequence-specific DNA binding transcription factor activity
defense response to virus
positive regulation of type I interferon-mediated signaling pathway
cellular response to exogenous dsRNA
positive regulation of chemokine (C-C motif) ligand 5 production
positive regulation of IP-10 production
regulation of peroxisome organization

Function(s)

signal transducer activity
protein binding
protein kinase binding
CARD domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR20000734.hg.1	ENST00000358134.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000734.hg.1	ENST00000428216.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000734.hg.1	NM_020746.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000734.hg.1	NR_037921.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000734.hg.1	TC20000043.hg.1	HTA TC