Hs00542478_m1

• Gene Symbol: KCNH2
• Gene Name: potassium voltage-gated channel subfamily H member 2
• Gene Aliases: ERG-1, ERG1, H-ERG, HERG, HERG1, Kv11.1, LQT2, SQT1
• Chromosome Location: Chr.7: 150944956 - 150978314 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: KCNH2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001204798.1	NP_001191727.1	1 - 2	436		82
	NM_172057.2	NP_742054.1	1 - 2	436		82
GenBank mRNA	AJ512214.1	-	1 - 2	127		82
	AJ609614.1	-	1 - 2	110		82
	BG683210.1	-	1 - 2	435		82
	BQ890248.1	-	1 - 2	434		82
	DQ120125.1	-	1 - 2	513		82

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0700013050.hg.1
This assay targets the same location as HTA transcript cluster(s) TC07002024.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Ion Channel, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene KCNH2

Panther Classification:

Molecular Function -

ion channel

Gene Ontology Categories:

Process(es)

phosphorelay signal transduction system
regulation of heart rate by hormone
signal transduction by protein phosphorylation
cellular response to drug
regulation of membrane potential
potassium ion homeostasis
cardiac muscle contraction
regulation of membrane repolarization
regulation of ventricular cardiac muscle cell membrane repolarization
cardiac conduction
potassium ion export
potassium ion transmembrane transport
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane repolarization during action potential
membrane repolarization during cardiac muscle cell action potential
regulation of heart rate by cardiac conduction
potassium ion export across plasma membrane
membrane repolarization during ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transport
negative regulation of potassium ion transmembrane transport
positive regulation of potassium ion transmembrane transport
negative regulation of potassium ion export

Function(s)

phosphorelay sensor kinase activity
inward rectifier potassium channel activity
voltage-gated potassium channel activity
delayed rectifier potassium channel activity
protein binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
C3HC4-type RING finger domain binding
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
scaffold protein binding
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization