Hs00766187_m1

• Gene Symbol: MCL1
• Gene Name: BCL2 family apoptosis regulator
• Gene Aliases: BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
• Chromosome Location: Chr.1: 150574551 - 150579738 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MCL1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_182763.2	NP_877495.1	1 - 2	894		88
GenBank mRNA	AF203373.1	-	1 - 2	686		88

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0100018484.hg.1
This assay targets the same location as HTA transcript cluster(s) TC01003205.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Apoptosis, Homo sapiens, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MCL1

Gene Ontology Categories:

Process(es)

cell fate determination
multicellular organism development
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
cellular homeostasis
response to cytokine
negative regulation of apoptotic process
protein transmembrane transport
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of anoikis
regulation of response to DNA damage stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
protein channel activity
protein homodimerization activity
protein heterodimerization activity
BH3 domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
ABI Human Genome Survey Microarray Version 2.0	147139	-	-