Hs00912399_g1

• Gene Symbol: KMT2D
• Gene Name: lysine methyltransferase 2D
• Gene Aliases: AAD10, ALR, CAGL114, KABUK1, KMS, MLL2, MLL4, TNRC21
• Chromosome Location: Chr.12: 49018975 - 49060884 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: KMT2D
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003482.3	NP_003473.3	27 - 28	5867		57
	XM_005269162.4	XP_005269219.1	28 - 29	7146		57
	XM_006719614.3	XP_006719677.1	28 - 29	7155		57
	XM_006719616.3	XP_006719679.1	28 - 29	7143		57
	XM_011538770.2	XP_011537072.1	28 - 29	7158		57
	XM_011538771.2	XP_011537073.1	28 - 29	7155		57
	XM_011538772.2	XP_011537074.1	28 - 29	7149		57
	XM_011538773.2	XP_011537075.1	28 - 29	7146		57
	XM_011538776.2	XP_011537078.1	28 - 29	7158		57
GenBank mRNA	AF010403.1	-	27 - 28	5042		57
	AF010404.1	-	18 - 19	4127		57

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1200012790.hg.1
This assay targets the same location as HTA transcript cluster(s) TC12003277.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene KMT2D

Gene Ontology Categories:

Process(es)

oocyte growth
chromatin silencing
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of cell proliferation
positive regulation of intracellular estrogen receptor signaling pathway
response to estrogen
positive regulation of transcription from RNA polymerase II promoter
oogenesis
histone H3-K4 methylation
beta-catenin-TCF complex assembly

Function(s)

DNA binding
protein binding
zinc ion binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
transcription regulatory region DNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR12019245.hg.1	TC12003277.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR12019245.hg.1	ENST00000301067.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR12019245.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203136.hg.1	ENST00000301067.11	Ensembl
Affymetrix Human Clariom D Assay	PSR1200203136.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203136.hg.1	ENST00000301067.11	Ensembl
Affymetrix Human Clariom D Assay	PSR1200203136.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203136.hg.1	TC1200012790.hg.1	Clariom D TC