Hs00912416_m1

• Gene Symbol: KMT2D
• Gene Name: lysine methyltransferase 2D
• Gene Aliases: AAD10, ALR, CAGL114, KABUK1, KMS, MLL2, MLL4, TNRC21
• Chromosome Location: Chr.12: 49018975 - 49060884 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: KMT2D
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003482.3	NP_003473.3	42 - 43	14001		65
	XM_005269162.4	XP_005269219.1	43 - 44	15280		65
	XM_006719614.3	XP_006719677.1	43 - 44	15289		65
	XM_006719616.3	XP_006719679.1	43 - 44	15277		65
	XM_011538770.2	XP_011537072.1	43 - 44	15292		65
	XM_011538771.2	XP_011537073.1	43 - 44	15289		65
	XM_011538772.2	XP_011537074.1	43 - 44	15283		65
	XM_011538773.2	XP_011537075.1	43 - 44	15280		65
	XM_011538774.2	XP_011537076.1	43 - 44	15272		65
	XM_011538776.2	XP_011537078.1	43 - 44	15199		65
GenBank mRNA	AB209494.1	-	9 - 10	5503		65
	AF010403.1	-	42 - 43	13176		65
	AF010404.1	-	33 - 34	12261		65

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1200012790.hg.1
This assay targets the same location as HTA transcript cluster(s) TC12003277.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene KMT2D

Gene Ontology Categories:

Process(es)

oocyte growth
chromatin silencing
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of cell proliferation
positive regulation of intracellular estrogen receptor signaling pathway
response to estrogen
positive regulation of transcription from RNA polymerase II promoter
oogenesis
histone H3-K4 methylation
beta-catenin-TCF complex assembly

Function(s)

DNA binding
protein binding
zinc ion binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
transcription regulatory region DNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR12019228.hg.1	TC12003277.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR12019228.hg.1	ENST00000301067.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR12019228.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203114.hg.1	ENST00000301067.11	Ensembl
Affymetrix Human Clariom D Assay	PSR1200203114.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203114.hg.1	ENST00000301067.11	Ensembl
Affymetrix Human Clariom D Assay	PSR1200203114.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203114.hg.1	TC1200012790.hg.1	Clariom D TC