Hs00927730_m1

• Gene Symbol: PIK3CB
• Gene Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
• Gene Aliases: P110BETA, PI3K, PI3KBETA, PIK3C1
• Chromosome Location: Chr.3: 138652698 - 138834938 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PIK3CB
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_006219.2	NP_006210.1	4 - 5	814		87
	XM_005247530.2	XP_005247587.1	6 - 7	1163		87
	XM_006713659.3	XP_006713722.1	5 - 6	1034		87
	XM_011512895.2	XP_011511197.1	7 - 8	1159		87
	XM_011512896.1	XP_011511198.1	3 - 4	479		87
	XM_017006619.1	XP_016862108.1	5 - 6	837		87
	XM_017006620.1	XP_016862109.1	3 - 4	479		87
	XM_017006621.1	XP_016862110.1	3 - 4	479		87
GenBank mRNA	BC114432.1	-	4 - 5	802	40008544	87
	S67334.1	-	4 - 5	798		87

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC03001824.hg.1

Additional Information:

This assay is in the 5'UTR region of the XM_017006620.1,XM_017006621.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PIK3CB

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

activation of MAPK activity
endothelial cell proliferation
regulation of cell-matrix adhesion
phosphatidylinositol biosynthetic process
cellular calcium ion homeostasis
autophagy
chemotaxis
homophilic cell adhesion via plasma membrane adhesion molecules
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of autophagy
positive regulation of gene expression
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
cell migration
platelet activation
phosphatidylinositol-3-phosphate biosynthetic process
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
embryonic cleavage
phosphatidylinositol phosphorylation
vascular endothelial growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
T cell receptor signaling pathway
leukocyte migration
angiogenesis involved in wound healing
platelet aggregation
regulation of clathrin-mediated endocytosis

Function(s)

protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol 3-kinase activity
1-phosphatidylinositol-4-phosphate 3-kinase activity
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR03033073.hg.1	TC03001824.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR03033073.hg.1	ENST00000289153.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03033073.hg.1	ENST00000477593.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03033073.hg.1	NM_006219.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR03033074.hg.1	TC03001824.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR03033074.hg.1	ENST00000289153.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03033074.hg.1	ENST00000477593.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03033074.hg.1	NM_006219.2	Refseq