Hs00931617_m1

• Gene Symbol: ARRB1
• Gene Name: arrestin beta 1
• Gene Aliases: ARB1, ARR1
• Chromosome Location: Chr.11: 75260122 - 75351831 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ARRB1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_020251.3	NP_064647.1	12 - 13	1222		102
	XM_011545035.2	XP_011543337.1	13 - 14	1106		102
	XM_017017751.1	XP_016873240.1	13 - 14	1106		102
	XM_017017754.1	XP_016873243.1	12 - 13	1062		102
GenBank mRNA	AF084940.1	-	12 - 13			102
	BX402200.2	-	3 - 4			102
	FJ348262.1	-	12 - 13	998		102

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC11002092.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ARRB1

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

activation of MAPK activity
positive regulation of protein phosphorylation
G-protein coupled receptor internalization
positive regulation of receptor internalization
transcription from RNA polymerase II promoter
apoptotic process
phototransduction
protein transport
protein ubiquitination
platelet activation
negative regulation of protein ubiquitination
positive regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
positive regulation of protein binding
negative regulation of interleukin-6 production
negative regulation of interleukin-8 production
positive regulation of peptidyl-serine phosphorylation
negative regulation of GTPase activity
positive regulation of smooth muscle cell apoptotic process
positive regulation of Rho protein signal transduction
positive regulation of histone acetylation
positive regulation of insulin secretion involved in cellular response to glucose stimulus
response to antidepressant
follicle-stimulating hormone signaling pathway
stress fiber assembly
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of histone H4 acetylation

Function(s)

histone acetyltransferase activity
enzyme inhibitor activity
GTPase activator activity
insulin-like growth factor receptor binding
protein binding
transcription factor binding
estrogen receptor binding
mitogen-activated protein kinase kinase binding
ubiquitin protein ligase binding
alpha-1A adrenergic receptor binding
alpha-1B adrenergic receptor binding
angiotensin receptor binding
follicle-stimulating hormone receptor binding
V2 vasopressin receptor binding
AP-2 adaptor complex binding
clathrin adaptor activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
transcription regulatory region DNA binding
ion channel binding
protein phosphorylated amino acid binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR11025068.hg.1	ENST00000360025.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11025068.hg.1	ENST00000393505.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11025068.hg.1	ENST00000420843.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11025068.hg.1	NM_004041.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11025068.hg.1	NM_020251.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11025068.hg.1	TC11002092.hg.1	HTA TC