Hs00940245_g1

• Gene Symbol: BAK1
• Gene Name: BCL2 antagonist/killer 1
• Gene Aliases: BAK, BAK-LIKE, BCL2L7, CDN1
• Chromosome Location: Chr.6: 33572546 - 33580293 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: BAK1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001188.3	NP_001179.1	1 - 2	271		71
	XM_011514780.1	XP_011513082.1	1 - 2	254		71
GenBank mRNA	AK091807.1	-	1 - 2	198		71
	AK303422.1	-	1 - 2	250		71
	BC004431.1	-	1	182	2819507	71
	BC110337.1	-	1 - 2	182	5755200	70
	CB142221.1	-	1 - 2	271		71
	U16811.1	-	1 - 2	171		71
	U23765.1	-	1 - 2	35		71
	X84213.1	-	1 - 2	163		71

More Information

Additional Information:

This assay is in the 5'UTR region of the AK091807.1, AK303422.1, BC004431.1, BC110337.1, NM_001188.3, U16811.1, U23765.1, X84213.1, XM_011514780.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene BAK1

Gene Ontology Categories:

Process(es)

B cell homeostasis
B cell apoptotic process
release of cytochrome c from mitochondria
blood vessel remodeling
myeloid cell homeostasis
B cell negative selection
activation of signaling protein activity involved in unfolded protein response
brain development
aging
mitochondrial fusion
cell proliferation
negative regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
response to fungus
response to mycotoxin
response to UV-C
establishment or maintenance of transmembrane electrochemical gradient
response to gamma radiation
positive regulation of calcium ion transport into cytosol
negative regulation of gene expression
response to organic cyclic compound
cytolysis
endocrine pancreas development
organ regeneration
endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum calcium ion concentration
negative regulation of peptidyl-serine phosphorylation
cellular response to UV
limb morphogenesis
response to drug
response to hydrogen peroxide
positive regulation of apoptotic process
regulation of protein homodimerization activity
regulation of protein heterodimerization activity
fibroblast apoptotic process
response to ethanol
positive regulation of proteolysis
regulation of mitochondrial membrane permeability
post-embryonic camera-type eye morphogenesis
regulation of cell cycle
regulation of mitochondrial membrane potential
vagina development
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
thymocyte apoptotic process
cellular response to mechanical stimulus
positive regulation of release of cytochrome c from mitochondria
apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
activation of cysteine-type endopeptidase activity
positive regulation of endoplasmic reticulum unfolded protein response
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
apoptotic process involved in patterning of blood vessels
positive regulation of IRE1-mediated unfolded protein response

Function(s)

protein binding
heat shock protein binding
identical protein binding
protein homodimerization activity
ion channel binding
metal ion binding
protein heterodimerization activity
chaperone binding
BH domain binding