Hs00967503_m1

• Gene Symbol: CHEK1
• Gene Name: checkpoint kinase 1
• Gene Aliases: CHK1
• Chromosome Location: Chr.11: 125624910 - 125676259 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: CHEK1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001114121.2	NP_001107593.1	3 - 4	1185		80
	NM_001114122.2	NP_001107594.1	3 - 4	1185		80
	NM_001244846.1	NP_001231775.1	3 - 4	1185		80
	NM_001274.5	NP_001265.2	3 - 4	528		80
	NR_045205.1		3 - 4	722		80
	XM_017017146.1	XP_016872635.1	3 - 4	372		80
GenBank mRNA	AB451222.1	-	2 - 3	288		80
	AB451345.1	-	2 - 3	288		80
	AF016582.1	-	2 - 3	322		80
	AF032874.1	-	2 - 3	288		80
	AK292549.1	-	3 - 4	722		80
	AK293143.1	-	3 - 4	350		80
	BC004202.2	-	3 - 4	347	3530606	80
	BC017575.1	-	3 - 4	446	4091997	80
	BP207812.1	-	4 - 5	490		80
	DA567616.1	-	3 - 4	419		80

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC11003470.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Protein Kinase, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene CHEK1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
G2/M transition of mitotic cell cycle
DNA replication
DNA repair
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
regulation of double-strand break repair via homologous recombination
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
peptidyl-threonine phosphorylation
G2 DNA damage checkpoint
histone H3-T11 phosphorylation
regulation of cell proliferation
negative regulation of mitotic nuclear division
regulation of mitotic centrosome separation
chromatin-mediated maintenance of transcription
cellular response to mechanical stimulus
replicative senescence
regulation of signal transduction by p53 class mediator
regulation of histone H3-K9 acetylation

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
histone kinase activity (H3-T11 specific)

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	TC11003470.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	ENST00000278916.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	ENST00000427383.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	ENST00000428830.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	ENST00000438015.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	ENST00000524737.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	ENST00000532449.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	ENST00000534070.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	ENST00000544373.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	NM_001114121.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	NM_001114122.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	NM_001244846.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	NM_001274.5	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	NR_045204.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11014656.hg.1	NR_045205.1	Refseq