Hs00969331_m1

• Gene Symbol: NEDD4L
• Gene Name: neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
• Gene Aliases: NEDD4-2, NEDD4.2, RSP5, hNEDD4-2
• Chromosome Location: Chr.18: 58044362 - 58401540 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: NEDD4L
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001144964.1	NP_001138436.1	26 - 27	2721		97
	NM_001144965.1	NP_001138437.1	26 - 27	2673		97
	NM_001144966.2	NP_001138438.1	25 - 26	2598		97
	NM_001144967.2	NP_001138439.1	26 - 27	2767		97
	NM_001144968.1	NP_001138440.1	26 - 27	2663		97
	NM_001144969.1	NP_001138441.1	25 - 26	2603		97
	NM_001144970.2	NP_001138442.1	24 - 25	2646		97
	NM_001144971.1	NP_001138443.1	26 - 27	2691		97
	NM_001243960.1	NP_001230889.1	24 - 25	2575		97
	NM_015277.5	NP_056092.2	25 - 26	2707		97
	XM_005266658.4	XP_005266715.2	23 - 24	2698		97
	XM_005266660.4	XP_005266717.2	22 - 23	2642		97
	XM_005266663.4	XP_005266720.2	21 - 22	2582		97
	XM_006722421.3	XP_006722484.2	22 - 23	2637		97
	XM_006722424.3	XP_006722487.2	19 - 20	2190		97
	XM_006722425.3	XP_006722488.2	18 - 19	2134		97
	XM_006722426.3	XP_006722489.1	28 - 29	2915		97
	XM_006722428.3	XP_006722491.1	27 - 28	2837		97
	XM_006722430.3	XP_006722493.1	26 - 27	2745		97
	XM_011525887.2	XP_011524189.1	28 - 29	2895		97
	XM_017025676.1	XP_016881165.1	20 - 21	2387		97
	XM_017025677.1	XP_016881166.1	19 - 20	2331		97
	XM_017025678.1	XP_016881167.1	26 - 27	2776		97
	XM_017025679.1	XP_016881168.1	25 - 26	2691		97
	XM_017025680.1	XP_016881169.1	22 - 23	2379		97
	XM_017025681.1	XP_016881170.1	21 - 22	2181		97
GenBank mRNA	AK294963.1	-	25 - 26	2598		97
	AK300444.1	-	25 - 26	2549		97
	AL137469.1	-	21 - 22	2019		97
	AY112983.1	-	26 - 27	2673		97
	AY112984.2	-	26 - 27	2663		97
	BC000621.2	-	20 - 21	2124		97
	BC019345.1	-	20 - 21	2124		97
	BC032597.1	-	24 - 25	2602	5528964	97
	BQ215431.1	-	5 - 6	331		97
	DQ181796.1	-	26 - 27	2691		97

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1800007411.hg.1
This assay targets the same location as HTA transcript cluster(s) TC18000202.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene NEDD4L

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
regulation of membrane depolarization
protein monoubiquitination
sodium ion transport
cellular sodium ion homeostasis
excretion
response to metal ion
protein ubiquitination
viral life cycle
water homeostasis
ion transmembrane transport
regulation of ion transmembrane transport
regulation of protein catabolic process
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process
positive regulation of endocytosis
regulation of membrane repolarization
protein K48-linked ubiquitination
ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transport
negative regulation of sodium ion transmembrane transport
positive regulation of dendrite extension
negative regulation of protein localization to cell surface
negative regulation of sodium ion transmembrane transporter activity
positive regulation of caveolin-mediated endocytosis

Function(s)

ubiquitin-protein transferase activity
protein binding
potassium channel regulator activity
ligase activity
sodium channel regulator activity
potassium channel inhibitor activity
sodium channel inhibitor activity
ion channel binding