Hs00989654_g1

• Gene Symbol: CCL21
• Gene Name: C-C motif chemokine ligand 21
• Gene Aliases: 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4
• Chromosome Location: Chr.9: 34709005 - 34710167 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: CCL21
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_002989.3	NP_002980.1	2 - 3	288		71
	XM_011518004.2	XP_011516306.1	2 - 3	275		71
GenBank mRNA	AB002409.1	-	2 - 3	245		71
	AF001979.1	-	2 - 3	187		71
	AK311901.1	-	2 - 3	257		71
	AY358887.1	-	2 - 3	192		71
	BC027918.1	-	2 - 3	194	5226781	71
	BI833188.1	-	2 - 3	270		71
	BP331359.1	-	2 - 3	288		71
	CR450326.1	-	2 - 3	187		71
	U88320.1	-	2 - 3	201		71

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC09001045.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene CCL21

Panther Classification:

Molecular Function -

cytokine, intercellular signal molecule

Gene Ontology Categories:

Process(es)

establishment of T cell polarity
immunological synapse formation
positive regulation of cell-matrix adhesion
dendritic cell chemotaxis
monocyte chemotaxis
positive regulation of dendritic cell antigen processing and presentation
inflammatory response
immune response
G-protein coupled receptor signaling pathway
cell-cell signaling
positive regulation of glycoprotein biosynthetic process
positive regulation of actin filament polymerization
positive regulation of pseudopodium assembly
T cell costimulation
ruffle organization
positive regulation of cell adhesion mediated by integrin
response to prostaglandin E
mesangial cell-matrix adhesion
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of protein kinase activity
positive regulation of JNK cascade
lymphocyte chemotaxis
positive regulation of receptor-mediated endocytosis
cell maturation
positive regulation of chemotaxis
release of sequestered calcium ion into cytosol
positive regulation of filopodium assembly
positive regulation of protein kinase B signaling
cell chemotaxis
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
positive regulation of neutrophil chemotaxis
activation of GTPase activity
dendritic cell dendrite assembly
negative regulation of leukocyte tethering or rolling
negative regulation of leukocyte apoptotic process
positive regulation of cell motility
positive regulation of T cell migration
positive regulation of myeloid dendritic cell chemotaxis
negative regulation of dendritic cell dendrite assembly

Function(s)

chemokine activity
CCR7 chemokine receptor binding
chemokine receptor binding
CCR chemokine receptor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR09013729.hg.1	TC09001045.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR09013729.hg.1	ENST00000259607.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09013729.hg.1	ENST00000378792.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09013729.hg.1	NM_002989.3	Refseq