Hs01009057_m1

• Gene Symbol: TCF7L2
• Gene Name: transcription factor 7 like 2
• Gene Aliases: TCF-4, TCF4
• Chromosome Location: Chr.10: 112950219 - 113167678 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TCF7L2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001146284.1	NP_001139756.1	6 - 7	1215		69
	NM_001198527.1	NP_001185456.1	6 - 7	1215		69
	XM_005270088.1	XP_005270145.1	6 - 7	1246		69
	XM_005270102.1	XP_005270159.1	7 - 8	1315		69
	XM_005270104.1	XP_005270161.1	6 - 7	1246		69
	XM_011540110.1	XP_011538412.1	7 - 8	1390		69
	XM_017016585.1	XP_016872074.1	8 - 9	1459		69
	XM_017016587.1	XP_016872076.1	8 - 9	1459		69
	XM_017016591.1	XP_016872080.1	7 - 8	1315		69
	XM_017016596.1	XP_016872085.1	7 - 8	1315		69
GenBank mRNA	BC032656.1	-	6 - 7	804	5533185	69
	FJ010165.1	-	6 - 7	747		69
	FJ010168.1	-	6 - 7	805		69
	HM352840.1	-	7 - 8	777		69
	HM352843.1	-	6 - 7	708		69

More Information

• Set Membership: Amplicon length less than or equal to 70, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell cycle arrest
Wnt signaling pathway, calcium modulating pathway
cell proliferation
response to glucose
positive regulation of heparan sulfate proteoglycan biosynthetic process
pancreas development
positive regulation of insulin secretion
positive regulation of protein binding
regulation of hormone metabolic process
glucose homeostasis
negative regulation of sequence-specific DNA binding transcription factor activity
maintenance of DNA repeat elements
canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
fat cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein export from nucleus
myoblast fate commitment
regulation of smooth muscle cell proliferation
positive regulation of protein kinase B signaling
canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway
beta-catenin-TCF complex assembly
negative regulation of type B pancreatic cell apoptotic process
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II repressing transcription factor binding
transcription factor activity, sequence-specific DNA binding
protein binding
beta-catenin binding
transcription factor binding
protein kinase binding
nuclear hormone receptor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
gamma-catenin binding
armadillo repeat domain binding