Hs01010934_m1

• Gene Symbol: EIF2AK4
• Gene Name: eukaryotic translation initiation factor 2 alpha kinase 4
• Gene Aliases: GCN2, PVOD2
• Chromosome Location: Chr.15: 39934101 - 40035596 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: EIF2AK4
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001013703.3	NP_001013725.2	14 - 15	2475		64
	XM_005254392.2	XP_005254449.1	14 - 15	2498		64
	XM_011521599.2	XP_011519901.1	14 - 15	2498		64
	XM_011521600.2	XP_011519902.1	14 - 15	2498		64
	XM_017022219.1	XP_016877708.1	14 - 15	2498		64
GenBank mRNA	AB037759.1	-	10 - 11	1941		64
	AL157497.1	-	3 - 4	272		64

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1500006930.hg.1
This assay targets the same location as HTA transcript cluster(s) TC15000272.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene EIF2AK4

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
adaptive immune response
T cell activation involved in immune response
positive regulation of adaptive immune response
regulation of translational initiation
protein phosphorylation
cell cycle arrest
learning
long-term memory
regulation of translational initiation by eIF2 alpha phosphorylation
viral translation
negative regulation of translational initiation in response to stress
negative regulation of CREB transcription factor activity
cellular response to amino acid starvation
cellular response to UV
eiF2alpha phosphorylation in response to endoplasmic reticulum stress
induction by virus of host autophagy
negative regulation by host of viral genome replication
negative regulation of neuron differentiation
negative regulation of translational initiation
protein autophosphorylation
defense response to virus
regulation of feeding behavior
regulation of eIF2 alpha phosphorylation by amino acid starvation
cellular response to cold
positive regulation of translational initiation in response to starvation
positive regulation of long-term synaptic potentiation
neuron projection extension
cellular response to leucine starvation

Function(s)

tRNA binding
protein serine/threonine kinase activity
eukaryotic translation initiation factor 2alpha kinase activity
ATP binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR15001744.hg.1	ENST00000263791.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR15001744.hg.1	ENST00000382727.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR15001744.hg.1	NM_001013703.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR15001744.hg.1	TC15000272.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1500148042.hg.1	ENST00000263791.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1500148042.hg.1	ENST00000560855.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1500148042.hg.1	NM_001013703.3	Refseq
Affymetrix Human Clariom D Assay	PSR1500148042.hg.1	ENST00000263791.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1500148042.hg.1	ENST00000560855.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1500148042.hg.1	NM_001013703.3	Refseq
Affymetrix Human Clariom D Assay	PSR1500148042.hg.1	TC1500006930.hg.1	Clariom D TC