Hs01041870_m1

• Gene Symbol: RIPK1
• Gene Name: receptor interacting serine/threonine kinase 1
• Gene Aliases: RIP, RIP-1, RIP1
• Chromosome Location: Chr.6: 3063888 - 3115187 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: RIPK1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001317061.1	NP_001303990.1	8 - 9	1348		106
	NM_003804.4	NP_003795.2	6 - 7	1070		106
	XM_005249457.3	XP_005249514.2	6 - 7	993		106
	XM_006715237.3	XP_006715300.2	6 - 7	993		106
	XM_017011403.1	XP_016866892.1	3 - 4	1102		106
	XM_017011405.1	XP_016866894.1	6 - 7	991		106
GenBank mRNA	AB208926.1	-	8 - 9	1257		106
	AK304701.1	-	4 - 5	659		106
	AK314176.1	-	6 - 7	1070		106
	BC126254.1	-	5 - 6	864	8991970	106
	BC126256.1	-	5 - 6	864	8991972	106
	U50062.1	-	5 - 6	838		106

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0600006653.hg.1
This assay targets the same location as HTA transcript cluster(s) TC06000023.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene RIPK1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
I-kappaB kinase/NF-kappaB signaling
activation of JUN kinase activity
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
positive regulation of necrotic cell death
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
tumor necrosis factor-mediated signaling pathway
response to tumor necrosis factor
TRIF-dependent toll-like receptor signaling pathway
peptidyl-serine autophosphorylation
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
cellular protein catabolic process
positive regulation of macrophage differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity
protein homooligomerization
protein heterooligomerization
positive regulation of necroptotic process
T cell apoptotic process
necroptotic process
regulation of ATP:ADP antiporter activity
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
death-inducing signaling complex assembly
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
ripoptosome assembly
necroptotic signaling pathway
ripoptosome assembly involved in necroptotic process
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of hydrogen peroxide-induced cell death
amyloid fibril formation
positive regulation of reactive oxygen species metabolic process
negative regulation of extrinsic apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

protein kinase activity
protein serine/threonine kinase activity
death receptor binding
protein binding
ATP binding
ubiquitin protein ligase binding
protein complex binding
identical protein binding
death domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR06000176.hg.1	TC06000023.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR06000176.hg.1	ENST00000259808.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR06000176.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR06000176.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR06000176.hg.1	ENST00000541791.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR06000176.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	PSR0600145572.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0600145572.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0600145572.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0600145572.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	PSR0600145572.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0600145572.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0600145572.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0600145572.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	PSR0600145572.hg.1	TC0600006653.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000259808.8	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000380409.2	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	ENST00000479389.1	Ensembl
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq
Affymetrix Human Clariom D Assay	TC0600006653.hg.1	NM_003804.5	Refseq