Hs01047568_g1

• Gene Symbol: STAT3
• Gene Name: signal transducer and activator of transcription 3
• Gene Aliases: ADMIO, ADMIO1, APRF, HIES
• Chromosome Location: Chr.17: 42313324 - 42388505 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: STAT3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003150.3	NP_003141.2	12 - 13	1362		124
	NM_139276.2	NP_644805.1	12 - 13	1384		124
	NM_213662.1	NP_998827.1	12 - 13	1276		124
	XM_005257616.3	XP_005257673.2	12 - 13	1375		124
	XM_005257617.3	XP_005257674.2	12 - 13	1370		124
	XM_011525145.2	XP_011523447.1	12 - 13	1375		124
	XM_011525146.2	XP_011523448.1	12 - 13	1375		124
	XM_017024972.1	XP_016880461.1	12 - 13	1370		124
	XM_017024973.1	XP_016880462.1	12 - 13	1375		124
	XM_017024974.1	XP_016880463.1	12 - 13	1370		124
	XM_017024975.1	XP_016880464.1	12 - 13	1363		124
	XM_017024976.1	XP_016880465.1	12 - 13	1363		124
GenBank mRNA	AB451232.1	-	11 - 12	1144		124
	AJ012463.1	-	11 - 12	1144		124
	AK291933.1	-	12 - 13	1457		124
	AK297994.1	-	11 - 12	1169		124
	AK301200.1	-	12 - 13	1292		124
	AK316139.1	-	12 - 13	1314		124
	BC000627.2	-	12 - 13	1281	3347434	124
	BC014482.1	-	12 - 13	1276	4909141	124

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1700010721.hg.1
This assay targets the same location as HTA transcript cluster(s) TC17001531.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene STAT3

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
temperature homeostasis
eye photoreceptor cell differentiation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
protein import into nucleus
movement of cell or subcellular component
acute-phase response
signal transduction
JAK-STAT cascade
nervous system development
aging
cell proliferation
negative regulation of cell proliferation
positive regulation of gene expression
negative regulation of hydrogen peroxide biosynthetic process
viral process
phosphorylation
cytokine-mediated signaling pathway
sexual reproduction
intracellular receptor signaling pathway
response to estradiol
cellular response to hormone stimulus
leptin-mediated signaling pathway
somatic stem cell population maintenance
miRNA mediated inhibition of translation
regulation of multicellular organism growth
response to drug
positive regulation of tyrosine phosphorylation of Stat3 protein
glucose homeostasis
eating behavior
negative regulation of apoptotic process
cellular response to leptin stimulus
response to leptin
response to ethanol
positive regulation of Notch signaling pathway
negative regulation of glycolytic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of mitochondrial membrane permeability
astrocyte differentiation
regulation of cell cycle
radial glial cell differentiation
regulation of feeding behavior
growth hormone receptor signaling pathway
JAK-STAT cascade involved in growth hormone signaling pathway
interleukin-6-mediated signaling pathway
cellular response to organic cyclic compound
energy homeostasis
negative regulation of neuron death
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
positive regulation of metalloendopeptidase activity
positive regulation of gene silencing by miRNA
positive regulation of ATP biosynthetic process
negative regulation of neuron migration

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II repressing transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
signal transducer activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
transcription factor binding
protein kinase binding
protein phosphatase binding
chromatin DNA binding
CCR5 chemokine receptor binding
glucocorticoid receptor binding
identical protein binding
transcription regulatory region DNA binding
protein dimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR17020464.hg.1	ENST00000264657.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR17020464.hg.1	ENST00000389272.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR17020464.hg.1	ENST00000404395.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR17020464.hg.1	NM_003150.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR17020464.hg.1	NM_139276.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR17020464.hg.1	NM_213662.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR17020464.hg.1	TC17001531.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	ENST00000264657.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	ENST00000389272.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	ENST00000404395.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	ENST00000585517.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	ENST00000588969.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	NM_003150.3	Refseq
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	NM_139276.2	Refseq
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	NM_213662.1	Refseq
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	ENST00000264657.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	ENST00000389272.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	ENST00000404395.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	ENST00000585517.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	ENST00000588969.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	NM_003150.3	Refseq
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	NM_139276.2	Refseq
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	NM_213662.1	Refseq
Affymetrix Human Clariom D Assay	PSR1700185206.hg.1	TC1700010721.hg.1	Clariom D TC