Hs01113395_m1

• Gene Symbol: SPO11
• Gene Name: SPO11, initiator of meiotic double stranded breaks
• Gene Aliases: CT35, SPATA43, TOPVIA
• Chromosome Location: Chr.20: 57329757 - 57343993 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: SPO11
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_012444.2	NP_036576.1	2 - 3	329		89
	XM_005260379.3	XP_005260436.1	2 - 3	347		89
	XM_005260380.3	XP_005260437.1	2 - 3	347		89
	XM_005260381.3	XP_005260438.1	2 - 3	347		89
	XM_005260382.4	XP_005260439.1	2 - 3	347		89
	XM_011528757.2	XP_011527059.1	2 - 3	181		89
GenBank mRNA	AF149310.1	-	2 - 3	269		89
	AF169385.1	-	2 - 3	344		89

More Information

Additional Information:

This assay is in the 5'UTR region of the XM_011528757.2 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene SPO11

Panther Classification:

Molecular Function -

DNA metabolism protein, endodeoxyribonuclease, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

DNA catabolic process, endonucleolytic
ovarian follicle development
synaptonemal complex assembly
reciprocal meiotic recombination
male meiosis I
spermatogenesis
spermatid development
female gamete generation
protein localization to chromosome
meiotic telomere clustering
oogenesis

Function(s)

DNA binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein binding
ATP binding
metal ion binding