Hs01561714_m1

• Gene Symbol: DOT1L
• Gene Name: DOT1 like histone lysine methyltransferase
• Gene Aliases: DOT1, KMT4
• Chromosome Location: Chr.19: 2163963 - 2232578 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: DOT1L
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_005259660.3	XP_005259717.1	28 - 29	5479		80

More Information

• Set Membership: Amplicon length between 71 and 85, Homo sapiens, Probe spans exons

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein, histone modifying enzyme

Gene Ontology Categories:

Process(es)

chromatin silencing
positive regulation of cell proliferation
telomere organization
histone H3-K79 methylation
positive regulation of transcription from RNA polymerase II promoter
regulation of JAK-STAT cascade
regulation of cell cycle
regulation of transcription regulatory region DNA binding

Function(s)

DNA binding
protein binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K79 specific)
histone methyltransferase activity